The vaccination procedure which is safe, well-tolerated, and induced a robust immune response in a Phase 1 first-in-human; As the GLS-5300 MERS CoV vaccine was well tolerating with no major side effects reporting by the volunteers. More than 85% of volunteers exhibiting a detectable immune response to MERS CoV after just two vaccinations. This vaccination…
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Gastroenteritis also known as infectious diarrhea, is inflammation of the gastrointestinal tract the stomach and small intestine; Symptoms may include diarrhea, vomiting and abdominal pain. Fever, lack of energy and dehydration may also occur. The enteric viruses associating with acute gastroenteritis; include rotavirus A, rotavirus B, rotavirus C, Caliciviruses; enteric adenovirus, human astroviruses, aichiviruses, toroviruses, coronaviruses, picobirnaviruses, enteroviruses, and Sali/Klassi viruses. Globally, RVA is the main cause of…
Studies of human monoclonal antibodies isolated from survivors of coronavirus-induced severe acute respiratory syndrome (SARS) or Middle-East respiratory syndrome (MERS) are unveiling surprising immune defense tactics against fatal viruses. Atomic and molecular information about the workings of the highly potent antibodies may provide insights to prevent these serious and sometimes deadly lung infections. Currently, no…
In the midst of an increasingly volatile Ebola outbreak in the Democratic Republic of Congo, a new study finds that the immune response generated by three experimental Ebola vaccines — including one already deployed in the DRC — persists for at least two and a half years. The study could have implications far beyond the Ebola fight.
What causes only a harmless cold in camels can be fatal for humans: an infection with the MERS virus. Since its discovery in 2012, the virus was detected in approximately 2,000 patients and 36 percent of them have not survived the severe lung disease known as MERS.
Researchers team reveals molecular structures developed a 3-D model based on the 1918 H1 pandemic influenza virus. Virus-like particles (VLPs) are protein-based structures that mimic viruses and bind to antibodies. Because VLPs are not infectious, they show considerable promise as vaccine platforms for many viral diseases, including influenza. The study was published in Scientific Reports, could benefit VLP vaccine projects, targeting a range of viruses from HIV to Ebola and SARS coronavirus.
Enrollment has begun in an early-stage clinical trial testing the safety of two human monoclonal antibodies (mAbs) designed to treat people infected with Middle East respiratory syndrome coronavirus (MERS-CoV).
A recently identified pig virus can readily find its way into laboratory-cultured cells of people and other species, a discovery that raises concerns about the potential for outbreaks that threaten human and animal health.
A newly identified coronavirus that killed nearly 25,000 piglets in 2016-17 in China emerged from horseshoe bats near the origin of the severe acute respiratory syndrome coronavirus (SARS-CoV), which emerged in 2002 in the same bat species.
The new virus, called swine acute diarrhea syndrome coronavirus (SADS-CoV), does not appear to infect people, unlike SARS-CoV. The research is published in the journal Nature.
Middle East respiratory syndrome (MERS) is a lethal disease in humans, caused by a coronavirus (MERS-CoV). It was first identified in man in 2012, in the Arabian Peninsula. The main MERS-CoV reservoir species is the dromedary, which is found in large numbers in many African countries. The first clues were published in an article in the journal PNAS on 5 March.
In this study, researchers examined the lethal disease in humans , Middle East respiratory syndrome (MERS) is a lethal disease in humans, caused by a coronavirus (MERS-CoV). It was first identified in man in 2012, in the Arabian Peninsula. The main MERS-CoV reservoir species is the dromedary, which is found in large numbers in many African countries. The study was published in the journal PNAS .
According to study, researchers evaluated the list of pathogens that could cause a worldwide pandemic is a mysterious addition: "Disease X." It was added to World Health Organization (WHO). The purpose of listing it is to inspire crosscutting research and development (R&D) efforts for well-known diseases that would be relevant for an as-yet-unknown disease, the WHO states.