A Dominant-Negative Effect With TP53 Mutations
The study find that A large team of researchers affiliated with several institutions in the U.S. and one in Germany has found evidence that makes a case for a dominant-negative effect with TP53 mutations. In their paper published in the journal Science, the group describes their study of such gene mutations and their work; which involved editing genes to test theorized outcomes, and what they learned. David Philip Lane with the Karolinska Institutet has published a Perspective piece in the same journal issue discussing the work; along with issues involved in reconciling the findings with those found in previous studies.
Breast Cancer Face Important Decisions About Their Surgical Treatment
The researches find that the Women newly diagnosed with breast cancer face important decisions about their surgical treatment. For many, those decisions are guide by cost. In a survey of more than 600 women with a history of breast cancer; 43% of respondents reported they considered costs when making treatment decisions; and one third reported that their cancer treatment created a financial burden that in some cases was catastrophic.
The Compartments And Complexity In The Eukaryotic Cell
The study showing the compartments and complexity in the cell; this showing the closer look at the subcellular distribution of the proteins; and metabolic intermediates in a model plant. The results of the study provide new insights into the dynamics of metabolic processes in cells. Eukaryotic cells in this context; plant cells contain a variety of subcellular compartments in which specific sets of enzymatic reactions take place.
Protein Combination Revealing New Drug Targeting For Viral Infections
According to the study deadly protein combination revealing new drug targeting for viral infections; these finding that how the two highly lethal viruses have greater pathogenic potential when their proteins are combining. Co-infections with these two viruses can occur in the same host, but we didn't know what would happen if their proteins combined. We discovered that not only could they work together, they can work even better than they do separately.
Encapsulating Two Drugs In Same Nanovector Improve Drug Delivery
The study find that the Encapsulating two drugs with different properties into nanovesicles surrounded by antibodies can greatly improve their delivery and efficacy, according to a study led by Xavier Fernández Busquets, director of the joint Nanomalaria unit at the Institute for Bionengineering of Catalonia (IBEC); and the Barcelona Institute for Global Health (ISGlobal), an institution supported by "la Caixa".