Neurodegeneration in Aging Renewed for a Second Phase


The researches find that the Neurodegeneration in Aging (CCNA); will be renew for a second phase, announce today. CCNA, the national component of the Government of Canada’s dementia research strategy; but brings together 311 researchers across the country to collaboratively investigate the diagnosis; therefore treatment and prevention of dementia and other age-related neurodegenerative diseases. Because CCNA is support by 11 other provincial partners and non-profit organizations. Baycrest will become CCNA’s scientific headquarters.

Neurodegeneration in Aging

This funding will support the continuing work of 19 research teams; which includes basic molecular research; but studies on the treatment and diagnosis of dementia and research looking at ways to improve the quality of life of individuals living with different forms of dementia. Therefore The second phase of CCNA includes the launch of a new national prevention platform; the Canadian Aging and Neurodegeneration Prevention Therapy Study Using Multidimensional Interventions for Brain Support – Unified Platform (CAN-THUMBS UP).

This large-scale study on dementia prevention will build on research accomplished during the first phase of CCNA to identify individuals at greater risk of dementia; and provide them an opportunity to undertake combination interventions to prevent its progression. CAN-THUMBS UP aligns with similar international studies in Sweden and the United States and through its results; CCNA aims to develop effective; but evidence-based dementia prevention strategies that can be implemented as part of public policy by 2029.

The Dementia prevention

There are at least 20 prevention strategies currently available that have the potential to slow cognitive decline and prevent various forms of dementia. An international study has shown that up to one third of dementia cases could be delay or prevented by managing certain health conditions. Therefore CCNA intends to make Canada a leader in dementia prevention by creating an infrastructure and a master protocol that can be used to test combination interventions; both pharmacological and non-pharmacological.”

“Researchers will closely monitor individuals involved in CAN-THUMBS UP to determine whether interventions can slow the progression of cognitive decline among older adults and delay the onset of symptoms”; adds Dr. Chertkow. Launched in 2014; CCNA’s first phase included setting up the world’s most in-depth study into different forms of dementia and the largest dementia study in Canada; therefore the Comprehensive Assessment of Neurodegeneration and Dementia (COMPASS-ND) study.

Certain health conditions

Through the study; extensive health data is being gathered from about 2,000 older adults with mild memory loss or various forms of dementia. This study aims to accelerate dementia research around the world by providing data that will contribute to a better understanding of Alzheimer’s disease and other neurodegenerative disorders; and assist in the development of ways to prevent, diagnose and delay the onset of dementia.