A study estimated that the effect of NOD on correlations between nasal and synonasal symptoms with clinical assessments of asthma control, 82 children, 9.8 [8.9; 10.7] years old, with atopic BA were assessed using ACQ-5 for the BA control level, TNSS for nasal symptoms, and SNOT-20 for synonasal quality of life in combination with rhinovideoendoscopy for NOD.
Bronchial asthma (BA) is the most common chronic disease of the respiratory system in children. According to the Global Initiative for Asthma (GINA), the goals of asthma treatment in children and adults are to minimize both the symptom burden and the risk of adverse asthma outcomes. Together, these two domains constitute asthma control.
In the present study, the comparison of the asthma control level estimated using the ACQ-5 questionnaire, and the expression of nasal symptoms (TNSS test) and the synonasal quality of life (SNOT-20 test) in patients of the two groups with the absence and presence of NOD, including anomalies of intranasal structures, hypertrophy of the pharyngeal tonsil, or a combination of these pathological conditions, were assessed.
The retention of nasal and synonasal symptoms, identified in the present study, in children with nasal obstructive disorders and with the achieved BA control should also be pointed out. This requires additional studying since the retention of nasal symptoms can potentially affect the quality of control achieved. Obviously, dynamic monitoring of the subsequent course of asthma in this group of patients is necessary in comparison with children who do not have nasal obstructive disorders.
This emphasizes the need for a unified approach to consideration of allergic inflammation of the upper and lower respiratory tract in BA children and demonstrates the importance of their simultaneous therapeutic correction. At the same time, the multimorbidity of the upper respiratory tract has a significant effect on this relationship.
In the conditions of achieved BA control in patients with multimorbid pathology of the upper respiratory tract, a higher level of expression of nasal and synonasal symptoms has been found. This requires close attention to the multimorbidity of nasal pathology in children with asthma and a careful studying for the effect of insufficient reduction of nasal and synonasal symptoms in children with multimorbid upper respiratory tract diseases on the control level and the course of BA in these patients.