Viruses such as measles and mumps not to mention the more serious HIV and Ebola; Human Cytomegalovirus can cause all kinds of health problems, research into the virus is also helping us harness the power of the human immune system to treat certain types of cancer.
As Human Cytomegalovirus is transmitting through bodily fluids such as urine, blood, saliva and breast milk; and the risk of being infecting is estimating to be 1% per annum; also estimating that every year one or two babies in every 200 are born with Human Cytomegalovirus; Up to 20% of babies who are infecting in utero die; and Human Cytomegalovirus is estimating to cause up to 12% of all sensorineural hearing loss; and 10% of cerebral palsy cases in newborns.
Human Immune System
For example mother is getting infecting for the first time while she is pregnant the risk of miscarriage; but still birth and the fetal hydrops a serious condition resulting in the abnormal accumulation of the fluid in the fetus are all increasing too.Human Cytomegalovirus infection also poses a major risk to children and adults.
But it is a common cause of death and disease in people suffering from AIDs; for people who have undergoing organ and bone marrow transplant and for those being treating with chemotherapy for cancer too; immune system is fully developed and functions well your body can keep the virus in check. This explains why HCMV can cause congenital defects fetuses; and newborns do not have fully functional immune systems so the virus can replicate and cause disease.
Human Cytomegalovirus viral replication
But in people having fully functional immune systems; Human Cytomegalovirus viral replication is controlling the infection; the virus has been infecting humans for 180 million years and during this time it has evolved many mechanisms that allow it to specifically evade or, more properly; “modulate” the immune system.
The ability of NK cells to eradicate tumour cells; and our growing understanding of what determines how these cells recognize their targets has led scientists to investigate the clinical efficacy of NK cells for immunotherapy. Now, new therapies are being developed which hope to use the anti-tumour targeting abilities of NK cells to treat cancers such as Acute Myeloid Leukaemia.