All news from Venereology

AIDS

STI Incidence Up: After Receipt of HIV Preexposure Prophylaxis

Emerging evidence suggests that risk of bacterial sexually transmitted infections (STIs); increases among gay and bisexual men; following initiation of HIV preexposure prophylaxis (PrEP). To describe STI incidence and behavioral risk factors; among a cohort of predominantly gay and bisexual men; who use PrEP, and to explore changes in STI incidence; following PrEP commencement. The…

AIDS

HPV Vaccination Rates Are Low, in HIV Prone Populations

The human papillomavirus (HPV) vaccine has reportedly led to a reduction in cancer-causing HPV prevalence; but uptake of the vaccination has been slow, despite the US Centers for Disease Control and Prevention (CDC). The CDC has been recommending that boys and girls up to the age of 15 receive the vaccine since 2006. However, it…

HIV/AIDS

Immunotherapy Kicks and Kills HIV

In a first on the quest to cure HIV, University of Pittsburgh Graduate School of Public Health scientists report in EBioMedicine that they’ve developed an all-in-one immunotherapy approach that not only kicks HIV out of hiding in the immune system, but also kills it. The key lies in immune cells designed to recognize an entirely…

AIDS

Text-based Counseling May Decrease HIV Risk

A mobile app created by a Rutgers researcher could be; used to improve the lives of LGBTQ people; who lack access to HIV prevention and education. Corina Lelutiu-Weinberger, a Rutgers School of Nursing assistant professor; recently introduced the first mobile program aimed at improving; the sexual, behavioral and mental health of gay and bisexual men;…

AIDS

Supporting HIV-affected Couples Trying to Conceive

Women with HIV were once; advised against having children for fear; that the infection could be; passed on to their babies. But medical advancements are not only allowing people with HIV; to live longer and fuller lives—but to grow their families; too. Timed vaginal insemination is a safe; effective way to help HIV-affected couples conceive,…

AIDS

Early Brain Atrophy From HIV Infection: Novel Brain Map Tracks

A new map of brain tissue in people with HIV shows atrophy in several areas including a primary neurocognitive control center; where shrinkage and loss of function can see in scans before clinical symptoms appear. The map and other findings from researchers at Georgetown University Medical Center; are published in the journal Human Brain Mapping.…

AIDS

HIV Infection Increases The Risk of Death

In a new study to investigate the relationship among depressive disorders or symptoms, HIV status and mortality, researchers report that symptoms of depression are moderately associated with death among Veterans with HIV but not among those without HIV infection. So, depression is the most frequently; reported mental health condition in people living with HIV in…

AIDS

Autoantibody Production in HIV-positive Patients

Human immunodeficiency virus, or HIV, attacks the immune system, making affected individuals more susceptible to infections. When patients with HIV, treated with antiretroviral therapy (ART), their immune system can recover, but some of them produce self-destructive proteins, or autoantibodies. Instead of attacking foreign invaders such as bacteria or viruses, some autoantibodies attack the body’s own…

AIDS

HIV Drug: Considered For Women in South Africa

Although a woman’s use of the HIV drug dolutegravir at conception may increase the risk of often-fatal neural tube defects in her child, a new study suggests that the risk may be offset by the drug’s ability to decrease deaths among women and prevent HIV transmission to their children and sexual partners. The report, led…

AIDS

First-ever Living Donor HIV-to-HIV Kidney Transplant

For the first time, a person living with HIV has donated a kidney to a transplant recipient also living with HIV. A multidisciplinary team from Johns Hopkins Medicine completed the living donor HIV-to-HIV kidney transplant. The doctors say both the donor and the recipient are doing well. This is the first time someone living with…

HIV

AIDS-immunocompromised Populations: Antibiotic-resistant Infections

The evolution of antibiotic resistance is far outpacing the development of new antibiotics, causing global public health concern about infections that will increasingly be unresponsive to antimicrobials. This risk of emerging antibiotic resistance may be meaningfully altered in highly AIDS-immunocompromised populations. Such populations fundamentally alter the bacterial evolutionary landscape in two ways, which we seek…

Tunneling towards better diagnosis

HIV/Tuberculosis Co-infection

The tuberculosis (TB) bacillus, Mycobacterium tuberculosis(Mtb), and HIV-1 act synergistically; however, the mechanisms by which Mtb exacerbates HIV-1 pathogenesis are not well known. Using in vitro and ex vivo cell culture systems, we show that human M(IL-10) anti-inflammatory macrophages, present in TB-associated microenvironment, produce high levels of HIV-1. In vivo, M(IL-10) macrophages are expanded in lungs of co-infected non-human primates, which correlates with disease severity. The…