Researchers have made a discovery about human papillomavirus (HPV) that could lead to new treatments for cervical cancer and other cancers caused by the virus, the most common sexually transmitted disease.
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Current HIV treatments need to be taken for life by those infected as antiretroviral therapy is unable to eliminate viral reservoirs lurking in immune cells. Institut Pasteur scientists have identified the characteristics of CD4 T lymphocytes that are preferentially infected by the virus – it is their metabolic activity1 that enables the virus to multiply. Thanks to metabolic activity inhibitors, the researchers have managed to destroy these infected cells, or "reservoirs", ex vivo. Their findings were published in the journal Cell Metabolism .
University of Nebraska-Lincoln researchers may have identified a vaccine that would defend against Zika virus without producing antibodies. Researcher Eric Weaver described the finding as exciting and novel. He and his team are confident that future experiments will yield significant findings that could have a profound impact on the field of vaccinology.
When people seek help at a drug treatment center for opioid addiction, concerns about having contracted hepatitis C are generally low on their list. They have often reached a crisis point in their lives, said Marie Sutton, the CEO of Imagine Hope, a consulting group that provides staff training and technical assistance to facilitate testing for the liver-damaging virus at more than 30 drug treatment centers in Georgia.
A key step in retroviral growth inside a cell, as described by Jamil Saad, Ph.D., and colleagues, is portrayed on the cover of The Journal of Biological Chemistry. It is a visual image, in molecular detail, of their journal article inside that looks at avian sarcoma virus or ASV.
The National Institute of Allergy and Infectious Diseases will fund a series of collaborations with medical research institutions in the southern United States to test new ways of HIV treatment and prevention tools in counties with some of the highest rates of new HIV cases nationwide.
Host genetic factors such as MBL2 gene polymorphisms cause defects in the polymerization of MBL protein and result in a functional deficiency and or in low serum levels that can influence susceptibility to various viral infections.
PLOS Distinct HIV-1 strains may differ like the CCR5 molecules to which they bind, affecting which cells they can infect and their ability to enter cells, according to a new study. The findings have implications for the development of HIV-1 entry inhibitors targeting CCR5.
Host genetic factors such as MBL2 gene polymorphisms cause defects in the polymerization of MBL protein and result in a functional deficiency and / or in low serum levels that influence susceptibility to various viral infections.
South African drugmaker Aspen Pharmacare launched a triple-combination tablet for the treatment of HIV in the country where the virus is most prevalent.
Updated draft recommendations from the U.S. Preventive Services Task Force support universal HIV screening in adolescents and adults, as well as preexposure prophylaxis (PrEP) with effective antiretroviral therapy for individuals at high risk of HIV acquisition.
A new study suggests that a genetic switch that causes latent HIV inside cells to begin to replicate can be manipulated to completely eradicate the virus from the human body. Cells harboring latent HIV are 'invisible' to the natural defenses of the immune system. The findings, which suggest a cure for HIV may be possible, are reported in the journal PNAS.