All news from Venereology

Destruction of HIV Reservoirs, New Approach

Current HIV treatments need to be taken for life by those infected as antiretroviral therapy is unable to eliminate viral reservoirs lurking in immune cells. Institut Pasteur scientists have identified the characteristics of CD4 T lymphocytes that are preferentially infected by the virus – it is their metabolic activity1 that enables the virus to multiply. Thanks to metabolic activity inhibitors, the researchers have managed to destroy these infected cells, or "reservoirs", ex vivo. Their findings were published in the journal Cell Metabolism .

Nebraska Virologists Discover Safer Potential Zika Vaccine

University of Nebraska-Lincoln researchers may have identified a vaccine that would defend against Zika virus without producing antibodies. Researcher Eric Weaver described the finding as exciting and novel. He and his team are confident that future experiments will yield significant findings that could have a profound impact on the field of vaccinology.

Hepatitis C And Drug Abuse Often Go Hand In Hand

When people seek help at a drug treatment center for opioid addiction, concerns about having contracted hepatitis C are generally low on their list. They have often reached a crisis point in their lives, said Marie Sutton, the CEO of Imagine Hope, a consulting group that provides staff training and technical assistance to facilitate testing for the liver-damaging virus at more than 30 drug treatment centers in Georgia.

MBL2 gene polymorphisms in HHV-8 infection

Host genetic factors such as MBL2 gene polymorphisms cause defects in the polymerization of MBL protein and result in a functional deficiency and or in low serum levels that can influence susceptibility to various viral infections. 

Eliminating the Latent Reservoir of HIV, Study

A new study suggests that a genetic switch that causes latent HIV inside cells to begin to replicate can be manipulated to completely eradicate the virus from the human body. Cells harboring latent HIV are 'invisible' to the natural defenses of the immune system. The findings, which suggest a cure for HIV may be possible, are reported in the journal PNAS.