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Influences Behind ART in HIV Positive Patients in Africa

An international team of researchers have carried out a review of the evidence examining what influences people who are HIV positive to go to health services and then stay on antiretroviral drugs in Africa. In a paper published in the Journal PLOS One the team, led by LSTM's Professor Paul Garner, used advanced methods of thematic synthesis to examine over 59 studies carried out in Africa, extracting key messages from the qualitative research.

Despite Slower Progression to AIDS, HIV-2 Is Deadlier, Finds Study

HIV-2 is more pathogenic than previously believed, and without treatment, most infected individuals will progress to HIV-related disease and death – although more slowly than they would with HIV-1, an international study has found. The authors say their study in The Lancet HIV, is the first to reliably estimate the time from HIV infection to AIDS or HIV-related death for HIV-2, with comparative estimates for both HIV-1-infected and HIV-negative individuals from the same population.

Role of Faulty Immune Receptor In HIV Complications

Scientists have discovered SLAMF7 , an immune receptor, called 'monocytes.' The finding was made after studying both healthy and HIV-infected patients. Yet, for certain HIV patients who experience a myriad of health issues, the researchers found that these patients' receptors do not work properly.

Effectiveness Of Efavirenz Pregnant HIV-Positive Women

Most of the 1.4 million pregnant women with HIV who received Antiretroviral Therapy in 2016 were given an EFV-based regimen, in line with World Health Organization recommendations, according to the researchers. While a number of studies found no increased risk following EFV exposure during the first trimester, case reports of birth defects – in particular, neural tube defects – and two small US studies reporting an increased risk associated with first-trimester use, prompted the current pooled analysis which suggests that EFV is at least as safe as other ART drugs currently recommended for antenatal use.

Pay-it-forward Model Increases STD testing Among Gay Men in China

Chinese gay men who were offered to free screening for gonorrhea and chlamydia and then asked to donate to the testing of another man were 48 percent more likely to get tested than men who were offered the standard of care. Researchers at the University of North Carolina at Chapel Hill's UNC Project-China site said their findings prove this pay-it-forward model could be used to expand other infectious diseases screening, like HIV testing, among gay men in China. Their results were published in  The Lancet Infectious Diseases.