An international team of researchers have carried out a review of the evidence examining what influences people who are HIV positive to go to health services and then stay on antiretroviral drugs in Africa. In a paper published in the Journal PLOS One the team, led by LSTM's Professor Paul Garner, used advanced methods of thematic synthesis to examine over 59 studies carried out in Africa, extracting key messages from the qualitative research.
All news from Venereology
HIV-2 is more pathogenic than previously believed, and without treatment, most infected individuals will progress to HIV-related disease and death – although more slowly than they would with HIV-1, an international study has found. The authors say their study in The Lancet HIV, is the first to reliably estimate the time from HIV infection to AIDS or HIV-related death for HIV-2, with comparative estimates for both HIV-1-infected and HIV-negative individuals from the same population.
Taking opioids raises the risk of pneumonia in individuals with and without HIV, a new Yale-led study finds. The study, published in JAMA Internal Medicine , reinforces the concern that prescription opioid painkillers have a negative impact on the immune system.
Scientists have discovered SLAMF7 , an immune receptor, called 'monocytes.' The finding was made after studying both healthy and HIV-infected patients. Yet, for certain HIV patients who experience a myriad of health issues, the researchers found that these patients' receptors do not work properly.
Most of the 1.4 million pregnant women with HIV who received Antiretroviral Therapy in 2016 were given an EFV-based regimen, in line with World Health Organization recommendations, according to the researchers. While a number of studies found no increased risk following EFV exposure during the first trimester, case reports of birth defects – in particular, neural tube defects – and two small US studies reporting an increased risk associated with first-trimester use, prompted the current pooled analysis which suggests that EFV is at least as safe as other ART drugs currently recommended for antenatal use.
Contraindicated statin use declined between 2007 and 2015 in HIV-infected adults treated with antiretroviral therapy (ART), while overall use remains suboptimal, researchers report.
The incidence of sexually acquired hepatitis C virus (HCV) infections appears to be rising among men who have sex with men (MSM) and use pre-exposure prophylaxis (PrEP) against HIV, US researchers report.
One in three people living with HIV in Vietnam remain undiagnosed, according to recent estimates. New strategies and models of HIV testing are urgently needed to reach undiagnosed populations and help them enroll in antiretroviral therapy (ART), in Vietnam and throughout the world.
Chinese gay men who were offered to free screening for gonorrhea and chlamydia and then asked to donate to the testing of another man were 48 percent more likely to get tested than men who were offered the standard of care. Researchers at the University of North Carolina at Chapel Hill's UNC Project-China site said their findings prove this pay-it-forward model could be used to expand other infectious diseases screening, like HIV testing, among gay men in China. Their results were published in The Lancet Infectious Diseases.
Thanks to the development of antiretroviral drugs, human immunodeficiency virus (HIV) is considered a manageable chronic disease today. However, if left undiagnosed or untreated, HIV can develop into AIDS (acquired immune deficiency syndrome), a disease which led to the deaths of nearly 1 million people worldwide in 2017. Study is published in the journal Cell Reports.
As Venezuela's hyperinflation and chronic medicine shortages leave HIV patients with little hope of obtaining antiretroviral drugs, many are now relying on the leaves of a tropical tree known as the guasimo.
New research shows that an experimental HIV vaccine strategy works in non-human primates. In the study, rhesus macaque monkeys produced neutralizing antibodies against one strain of HIV that resembles the viral resilient form that most commonly infects people, called a Tier 2 virus.