HIV Prevalence Of Detectable Viral Load An Indication

Some of the children born with HIV less likely to adhere to their medications; as they aging from preadolescence to adolescence and into young adulthood; Additionally, the prevalence of detectable viral load an indication that the virus is not being managing by medications; and a factor that often associating with nonadherence also increasing with age.

The study is one of the first to examine why different age groups stop adhering to treatment (nonadherence). While the factors related to nonadherence varied by age group; youth who were concerned about side effects of the drugs were less likely to be adherent at most ages. As they approach adulthood, many youth face challenges, such as entering new relationships; managing disclosure of their HIV status, and changing to an adult HIV care provider.

HIV prevalence of detectable viral

Ensuring successful HIV medication adherence before and throughout adolescence is critical. The study finding that the factors that either supported adherence and a suppressed (undetectable) viral load, or made it harder for youth to adhere to treatment; varying depending on their age. But approximately 12,000 children, adolescents, and young adults are living with perinatally acquired HIV, meaning that they have lived with HIV since birth.

Globally, 1.8 million adolescents live with HIV. Adhering to regimens of antiretroviral therapy (ART) is key to managing the disease and reducing the risk of transmission. Sticking to a daily regimen of medicine, however, is especially challenging for adolescents and young adults, who are navigating a range of physical, cognitive, social, and emotional changes. Adherence can be more complicated for youth growing up with perinatal HIV, whose lifelong experiences with HIV, stigma, and multiple antiretroviral medications may pose challenges to achieving viral suppression that are different from youth who acquire HIV later in life.

Participants in the pediatric HIV

To better understand these challenges and why young people may not adhere to their medications, researchers followed 381 youth with perinatally acquired HIV for an average of 3.3 years. The youth were participants in the Pediatric HIV/AIDS Cohort Study; which follows children and youth born with HIV or born exposed at birth to HIV; to determine the impact of lifelong HIV and the long-term safety of antiretroviral regimens.

For each age group, different factors were associated with nonadherence. For example, during middle adolescence (15-17 years old), alcohol use, having an unmarried caregiver; indirect exposure to violence, stigma, and stressful life events were all associated with nonadherence. It is important to talk with youth about how to take medications properly; but our study highlights the need for those who care for these youths to focus also on age-related factors that may influence adherence.