All news from Urology

Prostate

High-Grade Prostate Cancer Can By Treated by Popular Drugs

Man with enlarged prostate, can be treated with a type of drug called a 5-alpha reductase inhibitor (5-ARI). These drugs shrink the gland to improve urinary flow; and the approved forms used for treating enlarged prostates come in two varieties: Proscar (finasteride) and Avodart (dutasteride). However, a side effect of 5-ARI inhibitor treatment is that…

UTIs

UTIs Discovery May Lead To New Treatments

Sufferers of recurring urinary tract infections (UTIs) could expect more effective treatments thanks to University of Queensland-led research. UTIs are one of the most common bacterial infections according to Professor Mark Schembri from UQ’s School of Chemistry and Molecular Biosciences. “They are a major burden on global healthcare,” he said. “Approximately 25 % of women…

Prostate Cancer

Hormone Levels Not Associated With Lower Prostate Cancer Risk

Among men aged at least 70 years, type 2 diabetes appeared associated with a 35% reduction in risk for prostate cancer after consideration of standard risk factors, according to findings published in The Journal of Clinical Endocrinology & Metabolism. The longitudinal analysis of more than 3,000 men also showed that men with a history of diabetes;…

Radiation therapy

Radiation Therapy May Have Role In Oligometastatic Prostate Cancer

Radiation therapy (RT) can be effective for managing patients with oligometastatic prostate cancer (OPCa); according to investigators at Johns Hopkins University School of Medicine in Baltimore. A team led by Phuoc T. Tran, MD, PhD, based that conclusion on a study of 156 men with OPCa (median age 65.5 years) who underwent stereotactic ablative radiation…

Mortality Among Men With Prostate Cancer And Cardiovascular Disease

Mortality Among Men With Prostate Cancer And Cardiovascular Disease

Men with prostate cancer and pre-existing cardiovascular disease (CVD); have worse short-term mortality following treatment with oral androgen-signaling inhibitors than do similar men without CVD; according to a database study. “Approved cancer therapies do not always meet the therapeutic expectations promised in clinical trials because trials; usually exclude men with significant comorbidities or polypharmacy,” said…

Urinary tract infections

Need For Better Test To Diagnose Urinary Tract Infections

Doctors urgently need a fast and accurate test for diagnosing urinary tract infections (UTIs); to reduce overprescribing of antibiotics, according to health researchers. Dr Mar Pujades Rodriguez, from the University of Leeds; argues that without access to a reliable test doctors risk prescribing unnecessary antibiotic treatments; which increase the risk of antibacterial resistance. Current “bedside”…

UTIs

UTIs Discovery May Lead To New Treatments

Sufferers of recurring urinary tract infections (UTIs) could expect more effective treatments thanks to University of Queensland-led research. UTIs are one of the most common bacterial infections; according to Professor Mark Schembri from UQ’s School of Chemistry and Molecular Biosciences. “They are a major burden on global healthcare,” he said. “Approximately 25 % of women…

Radiotherapy

Radiotherapy Prolongs RFS For Certain Men With Prostate Cancer

Men with prostate cancer with positive surgical margins or extracapsular extension achieved longer biochemical RFS; after radical prostatectomy with adjuvant radiotherapy compared with surgery alone; according to results of a randomized Finnish study published in European Urology. Researchers observed the greatest benefit among men with pT2 disease and positive margins and those with Gleason scores…

Obesity

Obesity Tied To Worse Perioperative Outcomes Of Radical Prostatectomy

Obese men face higher odds of perioperative complications from radical prostatectomy, according to findings from a database study. Dr. Sophie Knipper of University Hospital Hamburg-Eppendorf, in Hamburg, Germany, and colleagues used data from the U.S. National Inpatient Sample database from 2008 to 2015 to investigate the effect of obesity (defined as a body mass index…

Urinary tract infections

Urinary Tract And Other Infections May Trigger Different Kinds Of Stroke

Several infections have identified as possible stroke triggers; with urinary tract infections showing the strongest link with ischemic stroke, according to new research in the American Heart Association’s journal Stroke. Previous research examined infections as triggers of stroke; but  limited to the correlation of acute infections with ischemic stroke; a type of stroke caused by…

Prostate Cancer

Elective Node Radiation Effective For Nodal-Recurrent Prostate Cancer

Elective nodal radiotherapy (ENRT) appears to reduce relapses better than stereotactic body radiotherapy (SBRT) in men with nodal oligorecurrent prostate cancer, according to a retrospective analysis. But ENRT is also more toxic, researchers report in European Urology, online. To compare outcome and toxicity between both treatments. Primary endpoint was metastasis-free survival, adjusted for selected variables.…

Testosterone-Blocking Drugs

Testosterone-Blocking Drugs Are Used to Treat Men With Prostate Cancer

Common testosterone-blocking drugs as a part of their treatment for many men with prostate cancer. However, those so-called anti-androgens also put them at risk for a deadly heart condition; new research. In a study published Monday in the American Heart Association journal Circulation, researchers looked at how several testosterone-blocking drugs affect the heart’s QT interval;…