Men who score high for the personality trait of neuroticism tend to have worse recovery and suffer from more adverse; events following radical prostatectomy than men with more with a more serene outlook on life; investigators reported here at the European Association of Urology (EAU) 2019 Congress. Neuroticism was by using the validated Eysenck Personality Questionnaire at a mean of 3 years after surgery.
Approximately one fifth (22%) of the 761 who answered scored high for neuroticism; these men had 21% higher severity scores for symptoms such as erectile dysfunction, urinary leakage; bowel problems than men with low neuroticism scores, said Karol Axcrona, MD, from Akershus University Hospital in Lørenskog, Norway.
This is significant in our opinion, and it is very; interesting since many men are offered radical treatment for their prostate cancer. In this instance, they analyzed patients operated on with radical prostatectomy; it would very interesting to analyze also patients treated with radical radiation therapy.
Developing somatic diseases
People with neuroticism are more susceptible to stressors, and might susceptible to developing somatic diseases and mental disorders such as depression in response to these stresses. For example, neuroticism is to exacerbate conditions such as inflammatory bowel disease and ulcerative colitis in some patients and to influence urinary symptoms and sexual function.
Axcrona and colleagues sent surveys to 982 men who had radical prostatectomies; at the Oslo University Hospital from 2005 through 2010 and based their study on responses from 761 men who reported adverse events and who responded to the neuroticism questionnaire.
Compared with men who reported low neuroticism; the men with high neurotic scores reported significantly more overall comorbidities (P = .006) and significantly worse scores in the EPIC-26 urinary domain (P < .001), including incontinence and irritation subscales (P < .001) for each. Men who scored high on neuroticism also fared less well in bowel problems (rectal urgency, loose/liquid stools, fecal incontinence; bloody stools, rectal pain; P < .001 for overall bowel problems).
Men with high neurotic scores
Similar results seen in the sexual problems domain; men with high neurotic scores had more trouble with erections and had difficulty achieving orgasm (P < .001 for overall sexual problems). In the hormonal domain, men with high neurotic scores reported having significantly more hot flashes, breast problems, depression, lack of energy, and weight change (P < .001 for all).
Porter’s center takes a multidisciplinary approach to the care of patients with prostate cancer; including a psychologist and social workers who can intervene when there are concerns about the potential health effects of a patient’s personality, he said, The neuroticism trait could a vulnerability factor for depression; of course, so this would a way to find some of those patients who are at most at risk.