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Transfusion medicine

Bone Marrow Transplants Of Hematopoietic Stem Cells

The researches find that the Bone marrow transplants of hematopoietic stem cells have become standard treatment for a host of conditions including cancers of the blood and lymphatic systems, sickle cell anemia, inherited metabolic disorders, and radiation damage. Unfortunately; many bone marrow transplants fail due to rejection by the patient’s immune system or graft-versus-host disease…

Transfusion medicine

Anticoagulant Choice in Severe Kidney Disease

The researches find that the oral anticoagulants (NOACs) offer a significantly lower stroke risk and an overall more favorable risk profile than vitamin K antagonists, such as warfarin, in patients with early stage chronic kidney disease (CKD), suggests a systematic review. However, the impact of the novel agents is unclear in patients with severe kidney disease. The oral…

Transfusion medicine

Helping Transplanted Stem Cells Stick Around

The researches find that the Bone marrow transplants of hematopoietic stem cells have become standard treatment for a host of conditions including cancers of the blood and lymphatic systems;  sickle cell anemia, inherited metabolic disorders, and radiation damage. Unfortunately, many bone marrow transplants fail due to rejection by the patient’s immune system or graft-versus-host disease…

Transfusion medicine

Liver Transplant Offers Advantages Over Deceased Transplant Liver Donor

The researches find that the Liver transplant offers numerous advantages over deceased-donor transplant, including better three-year survival rates for patients and lower costs, according to new research from the UPMC Thomas E. Starzl Transplantation Institute and the University of Pittsburgh School of Medicine. The findings; published online today in the Annals of Surgery; highlight living…

Transfusion medicine

Medicare Covered kidney Transplant Recipients

The study find that the Medicare’s lifetime immunosuppressant coverage after transplantation. He recalls the financial counselor saying; “Even after your insurance pays, you will still have to pay $215 every month for the medications. Can you afford that?” In this issue of American Journal of Transplantation, Hart and colleagues suggest that the answer to this…

Transfusion medicine

The Body’s Bone Marrow and Immune System With Chemotherapy

The researches find that the a stem cell transplant, this procedure replaces damaged or diseased bone marrow with healthy cells. The process involves wiping out the body’s bone marrow and immune system with chemotherapy and sometimes radiation. Then healthy donor cells are infused intravenously into the bloodstream so new cells can grow. Body’s bone marrow Bone marrow transplants often…

Pharmacology

Cancer-killing Agents Shows Promise in Destroying Cancer Cells

The study find that the a commonly used chemotherapy drug have discovered an entirely new class of cancer-killing agents that show promise in eradicating cancer stem cells. Their findings could prove to be a breakthrough in not only treating tumors; but ensuring cancer doesn’t return years later  giving peace of mind to patients that their…

Transfusion medicine

T-Cell Therapy and Hematopoietic Stem Cell Transplantation

The researches find that the  a naturally occurring antioxidant to modulate T cells of the immune system. This may be a big step towards improving currently used immune therapies such as adoptive T-cell therapy (ACT) and hematopoietic stem cell transplantation (HSCT). The studies are find by the National Institutes of Health led by Shikhar Mehrotra…

Transfusion medicine

Hematological Cancers Increase Long-Term Risk of Blood Clots

The researches find that the Patients with hematological cancers have a greater likelihood of experiencing serious complications, such as blood clot and bleeding events, according to a new study in the Journal of Thrombosis and Haemostasis. Hematological malignancies comprise a heterogeneous group of cancers, with different etiologies, treatments, and prognoses. Based on data from CONCORD-3…

Transfusion medicine

New Drug to Remove Blood Thinning Medication Post-Surgery

The researches find that the a new way to safely remove a blood thinning drug used during surgery that can lead to harmful side-effects in recovering patients. Heparin is a drug used during major surgery for blood thinning, however, once surgery is complete, the heparin must be removed so clotting, and healing, can begin. A blood-thinning…

Transfusion medicine

T Cells Autologous Transplantation in Poor Risk

High-dose chemotherapy followed by autologous stem cell transplantation (HDT-ASCT) is the standard of care for relapsed or chemo refractory diffuse large B-cell lymphoma (rel/ref DLBCL). Only 50% of patients are cured with this approach. We investigated whether CD19-specific chimeric antigen receptor (CAR) T cells administered following HDT-ASCT may enhance progression-free survival (PFS). Eligibility for this…

Transfusion medicine

Transplant-Associated Thrombotic Microangiopathy in Patients

The researches find that the Hematopoietic cell transplant (HCT), a curative option for patients with sickle cell disease (SCD), may be associated with a high risk of endothelial injury related complications such as posterior reversible encephalopathy syndrome (PRES), veno-occlusive disease (VOD), and transplant-associated thrombotic microangiopathy (TA-TMA). Chronic hemolysis in SCD leads to release of erythrocyte…