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Transfusion medicine

Blood Forming Stem Cells Facilitate Mobilization Procedures

Scientists at Winship Cancer Institute of Emory University, Children’s Healthcare of Atlanta and Georgia Tech have found that modulating blood-forming stem cells’ stiffness could possibly facilitate mobilization procedures used for stem cell-based transplants. Temporary squishiness could help drive blood forming stem cells out of the bone marrow and into the blood, but the cells need…

Transfusion medicine

IgG Antibodies Play Unexpected Role In Atherosclerosis

Researchers at Karolinska Institutes in Sweden have found that type IgG antibodies play an unexpected role in atherosclerosis. A study on mice shows that the antibodies stabilize the plaque that accumulates on the artery walls, which reduces the risk of it rupturing and causing a blood clot. It is hope that the results, which are…

Transfusion medicine

Younger Female Blood Donors Vulnerable To Iron Deficiency

Blood donation is associated with iron deficiency among both adolescent girls and younger adult women in the United States, according to a study recently published in Transfusion. Eshan U. Patel, M.P.H., from the Johns Hopkins University School of Medicine in Baltimore, and colleagues used data from the 1999 to 2010 National Health and Nutrition Examination Survey…

Transfusion medicine

Squishing Blood Stem Cells Facilitate Harvest For Transplants

Scientists at Winship Cancer Institute of Emory University, Children’s Healthcare of Atlanta and Georgia Tech have found that modulating blood-forming stem cells’ stiffness could possibly facilitate mobilization procedures used for stem cell-based transplants. Temporary squishiness could help drive blood-forming stem cells out of the bone marrow and into the blood, but the cells need to be stiff…

Transfusion medicine

Sensor Isolates Hidden Leukemic Stem Cells

All stem cells can multiply, proliferate and differentiate. Because of these qualities, leukemic stem cells are the most malignant of all leukemic cells. Understanding how leukemic stem cells are regulated has become an important area of cancer research. A team of Tel Aviv University researchers has now devised a novel biosensor that can isolate and…

Transfusion medicine

New Insights Into Rejection Of Transplanted Organs

Rejection of any kind is always hard to deal with, but when one’s body rejects a precious organ transplant, the consequences can be devastating. Professor A. Vathsala, Co-director of the National University Centre for Organ Transplantation at the National University Hospital (NUH) and Professor of Medicine; shared that between 30% to 40% of kidney transplants…

Transfusion medicine

Novel System To Measure Platelet Function

Emergency room doctors often have only a few minutes to determine which patients are in need of a blood transfusion. But currently doctors have no direct method to assess the health of one of the most critical component of the blood platelets. These tiny blood cells play a huge role in helping blood clot after…

Transfusion medicine

Infections Traced To Blood Shedding Religious Ritual

Researchers said Wednesday that they are initially puzzle how 10 British men had become infect with a little-known virus, because the men hadn’t taken risks usually associate with the disease. But then investigators learn they had participate in blood-shedding religious rituals cutting or whipping themselves in Iraq, Pakistan, India and the United Kingdom. Develop symptoms…

blood transfusion

New Method To Assess Platelet Health Could Help ER Doctors

Emergency room doctors often have only a few minutes to determine which patients are in need of a blood transfusion But currently doctors have no direct method to assess the health of one of the most critical component of the blood platelets. These tiny blood cells play a huge role in helping blood clot after an injury.…

Transfusion medicine

Older Stored Blood Transfusions And Bacterial Pneumonia

Human blood from donors can be stored for use up to 42 days, and it is a mainstay therapy in transfusion medicine. However, recent studies looking back at patient records have shown that transfusion with older; stored blood is associated with adverse effects. For severely injured patients who have massive bleeding and receive many transfusion…

Transfusion medicine

Blood Holds Key To Liver Regeneration

The liver is the only organ in the body that can regenerate. But some patients who undergo a liver resection, a surgery that removes a diseased portion of the organ, end up needing a transplant because the renewal process doesn’t work. A new Michigan State University study; published in the journal Blood, shows that the…

Blood Clots

Platelet Prevent Blood Clots Without Spreading Cancer

Like Jekyll and Hyde, the platelets in your blood are both good and evil. These specialized blood cells halt bleeding and help reconstruct injured tissue. But they can also cause dangerous blood clots and protect cancer cells as they travel from one site to another. Now, a team of bioengineers has taken the first step…