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Transfusion

A ‘Super-Cool’ Method For Improving Donated Liver Preservation

The study find that the a new method for super-cooling human donor livers to subzero centigrade temperatures without freezing can triple the time that a donor organ stays safe and viable during transportation from the donor to the recipient. This development could greatly expand the availability of healthy livers for transplantation, improve organ utilization, and…

Transfusion medicine

Synergistic Connection Between Two Deadly Blood-Clotting Diseases

The researches find that the blood-clotting diseases, namely thrombotic thrombocytopenic purpura, or TTP, and hemolytic uremic syndrome, or HUS, show similar pathologies a multitude of painful blockages in small blood vessels that cause varying degrees of organ injury throughout the body. However, the two disorders have distinct biological mechanisms. Therefore Now, in a preclinical study…

Transfusion Medicine

A Blood Clot In A Deep Vein Usually In The Legs Is Dislodged

The researches find that the most common cause of cardiovascular death in Europe, after heart attack and stroke, contributing to more than 350,000 deaths each year. A blood clot (thrombus) in a deep vein, usually in the legs, is dislodged and travels to the lungs where it blocks one or more vessels. Therefore This typically…

Transfusion medicine

Blood-Clotting Disorders With Different Causes Interact Synergistically

The study find that the potentially deadly blood-clotting diseases, namely thrombotic thrombocytopenic purpura, or TTP, and hemolytic uremic syndrome, or HUS, show similar pathologies a multitude of painful blockages in small blood vessels that cause varying degrees of organ injury throughout the body. However, the two disorders have distinctbiological mechanisms. Now, in a preclinical study…

Transfusion medicine

AFIRE Encourages Less Antiplatelet Use With NOACs In Stable

The researches find that the oral anticoagulation with vs without an antiplatelet agent in patients with both atrial fibrillation (AF) and stable coronary artery disease (CAD). In such patients with or without a history of revascularization, use of a novel oral anticoagulant (NOAC) alone was “noninferior” to the NOAC plus an antiplatelet agent for a…

Transfusion medicine

Transplanting Hep C-Infected Kidneys To Uninfected Donors Safe

The study find that the transplantation of kidneys from Hepatitis C-infected donors to uninfected recipients is safe and can be successfully implemented as a standard of care, according to an observational study by physicians at the University of Tennessee Health Science Center and the James D. Eason Transplant Institute at Methodist University Hospital. Therefore The…

Transfusion medicine

The Optimal Duration Of Dual Antiplatelet Therapy For Minor Stroke

The researches find that the dual antiplatelet therapy with clopidogrel and aspirin resulted in a net benefit vs aspirin alone when balancing the risks of a recurrent stroke against a hemorrhagic event; pooled data from two randomized, double-blind studies suggests. The analysis used individual patient-level data on more than 10,000 participants in the previously reported CHANCE and POINT…

Transfusion medicine

Stem-Cell Transplant Boosts Event-Free Neuroblastoma Survival

The study find that the tandem autologous stem-cell transplant (ASCT) may provide better event-free survival (EFS) in patients with high-risk neuroblastoma, compared with single ASCT, a new clinical trial shows. Therefore “Although it was our hypothesis that tandem transplant would decrease risk for recurrence, we were surprised by the positive results, including the magnitude of…

Transfusion Medicine

Psychosocial Outcomes 3 Years After Uterus Donation For Transplantation

The researches  find that the Uterus transplantation (UTx) is a quality-of-life enhancing transplantation and the first available treatment for absolute uterine factor infertility (AUFI), which affects around 20 000 women of fertile age in a general population of 100 million (Milliez, 2009; Sieunarine et al., 2005). The success of this type of transplantation was initially…