All news from Thoracic Medicine

Lung Cancers Is Top Leading Cause Of Death In Human Population

Lung Cancers Is Top Leading Cause Of Death In Human Population

Somatic mutations of MET gene are emerging as important driver mutations for lung cancers. To identify the common clinicopathological features of MET exon 14 skipping mutations and amplification and clarify whether the two MET gene alterations cause protein overexpression were investigate by using 196 lung cancer samples of Taiwan through real time-qPCR/sequencing, fluorescence in situ hybridization, and immuno histochemistry. The…

Lung Adenocarcinoma Is Most Common Type Of Lung Cancer

Lung Adenocarcinoma Is Most Common Type Of Lung Cancer

Known for its poor prognosis, lung adenocarcinoma is the most common type of lung cancer, responsible for about 4 of 10 diagnoses, according to the National Cancer Institute. Researchers on Mayo Clinic’s Florida campus can now distinguish between two pathways where this deadly cancer can develop. They say their discovery could help future patients. The…

Lung Cancer Is The Second Most Common And Deadliest Cancer

Lung Cancer Is The Second Most Common And Deadliest Cancer

Lung cancer claims more lives than any other type of cancer, having accounted for 11.6% of incident cancer cases and 18.4% of cancer deaths worldwide in 2018. Over half of these incidences and disease specific mortalities occurred in Asia. Within the region, the burden of lung cancer is mostly carried by East Asia, where the…

Smoking Might Affect Post Embolization PAVM Persistence Rates

Smoking Might Affect Post Embolization PAVM Persistence Rates

Smoking reduces the chances of a successful procedure to treat blood vessel abnormalities in the lungs; according to a study publish in the journal Radiology. Pulmonary arteriovenous malformations (PAVMs) are abnormal connections between arteries and veins in the lungs. The abnormalities; so can become symptomatic and lead to potentially dangerous complications. PAVMs are strongly associate…

Treatment For Systemic Sclerosis Associated Interstitial Lung Disease

Treatment For Systemic Sclerosis Associated Interstitial Lung Disease

The US Food and Drug Administration’s (FDA’s) Arthritis Advisory Committee has recommended approval of nintedanib (Ofev, Boehringer Ingelheim) for the treatment of systemic sclerosis associated interstitial lung disease (SSc-ILD). The committee voted 10 to 7 that the data did provide substantial evidence of nintedanib’s efficacy for SSc-ILD, and 14 to 2 (with 1 abstention) that the safety…

Targeted Treatment Identified For Lung Cancer

New Targeted Treatment Identified For Lung Cancer

The vast majority of deadly lung cancer cases (85%) are termed non-small-cell lung carcinomas (NSCLCs); which often contain a mutated gene called LKB1. Salk Institute researchers have now discovered precisely why inactive LKB1 results in cancer development. The surprising results, published in the online version of Cancer Discovery on July 26, 2019, highlight how LBK1…

Lung Cancer Screening Eligibility Should Be Expanded

Lung Cancer Screening Eligibility Should Be Expanded

Lung cancer; U.S. Preventive Services Task Force (USPSTF) eligibility criteria; so for lung-cancer screening should be expanded to cover other risk groups, researchers say based on findings from an observational study. “The current USPSTF should consider expanding the lower age limit to 50 years and extending years of quitting smoking for former smokers,” Dr. Ping…

Therapeutic Benefits For Patients With Non Small Cell Lung Cancer

Therapeutic Benefits For Patients With Non Small Cell Lung Cancer

Lung Cancer; Now, a new Salk Institute study, published on July 24, 2019, in the journal Science Advances, shows that researchers could target these hard-to-treat cancers by pursuing drugs that keep a cellular “switch,” called CREB, from triggering tumor growth. The study was led by Marc Montminy, professor and J.W. Kieckhefer Foundation Chair at Salk,…

Breast Cancer Research Could Expand Lung Cancer Therapies

Breast Cancer Research Could Expand Lung Cancer Therapies

New research into a genetic mutation’s role in breast cancer could open new treatment options for lung cancer, according to a Michigan State University scientist. “They sequenced the whole genome of breast cancer samples and find a driving mutation that hasn’t recognized as important in lung cancer before,” said Eran Andrechek, a College of Human…

Changed Treatment For Patients With Non Small Cell Lung Cancer

Changed Treatment For Patients With Non Small Cell Lung Cancer

Recent years have brought landmark changes for the treatment of patients with non-small cell lung cancer (NSCLC), though there are still many unanswered questions that remain, especially when it comes to frontline treatment strategies, according to Lecia V. Sequist, MD, MPH. One of the big clinical questions when you have a patient who is a…

Respiratory Function In Children With Cystic Fibrosis

Respiratory Function In Children With Cystic Fibrosis

Respiratory Function; Palivizumab a monoclonal antibody that prevents respiratory syncytial virus, or RSV, in high risk infants did not improve long-term outcomes like respiratory function in children with cystic fibrosis. The AAP does not recommend routine use of palivizumab for RSV prophylaxis in young children with cystic fibrosis (CF). However, the academy recommends that children…

Lung Cancer Screening May Mean Fewer Deaths From The Disease

Lung Cancer Screening May Mean Fewer Deaths From The Disease

The newer form of lung cancer screening may mean fewer deaths from the disease, a new study contends. Using low-dose compute tomography (LDCT) instead of X-rays help reduce lung cancer deaths in current and former smokers, the study authors said. “Lung cancer is the leading cause of cancer death worldwide, and early detection and treatment through…