All news from Thoracic Medicine

Root Causes of Asthma in Puerto Rico Addressed, Grant Provided

Researchers at the University of California, San Francisco (UCSF), National Jewish Health and Pediatric Pneumology Center in Puerto Rico have been awarded nearly $ 10 million as part of a 5-year grant from the US National Heart Lung and Blood Institute, where asthma prevalence and deaths are among the highest in the world. The team plans to follow the children from birth through early childhood to study how genes and viral infections affect respiratory disease.

Mucus: Can Scientists Change its Properties to Limit Harm to Lungs?

For healthy people, mucus is our friend. It traps potential pathogens so our airways can dispatch nasty bugs before they cause harm to our lungs. But for people with conditions such as cystic fibrosis (CF) and chronic obstructive pulmonary disorder (COPD), mucus can get too thick and sticky; coughing alone can not clear it Infections develop, leading to severe chronic disease and early death.

Now, for the first time, scientists at the UNC School of Medicine and Duke University demonstrated why coughing often can not tear mucus apart and away from the airway lining. And they showed how to make mucus thinner and less sticky so coughing can become a therapeutic aid.

Cystic Fibrosis: Patients May Receive Insufficient Antibiotics to Fight Lung Infections

The majority of patients with cystic fibrosis may not achieve blood concentrations of antibiotics sufficiently high enough to effectively fight bacteria responsible for pulmonary exacerbations, leading to worsening pulmonary function, indicates a study led by researchers. Additionally, the study findings show that it's impossible to predict solely from dosing regimens which patients will achieve therapeutically meaningful antibiotic concentrations in their blood.