All news from Rheumatology

Drug coverage

CMS Rule On Drug Coverage Policies For Rheumatoid Arthritis Therapies

The federal government has backed off a proposal that would have let Medicare Part D prescription drug plans; deny coverage for therapies in six “protected” classes of drugs, including those for cancer and psychiatric conditions. While that is seeing win for many consumers, patients, and physician groups; the Centers for Medicare & Medicaid Services‘ (CMS)…

Rheumatoid Arthritis

Zilucoplan May Decrease Symptoms of Generalized Myasthenia Gravis

A collaborative study has identified a new molecular mechanism causing rheumatoid arthritis. The researchers found that death of macrophages, an immune cell type, can trigger the disease. Moreover, they discovered how the protein A20 prevents macrophage death and protects against arthritis. These findings open up new possibilities for the treatment of this debilitating disease. Understanding…

Mast cells

Mast cells: Crucial To Causing Osteoarthritis

Stanford University School of Medicine scientists have definitively linked mast cells; a class of cells belonging to the immune system, to the development of osteoarthritis, one of the world’s most common causes of pain and immobility. Osteoarthritis, by far the most frequently occurring variety of arthritis; is by cartilage breakdown and inflammation in joints, which…

Chikungunya virus

Chikungunya: Drugs Vaccines For Viral Arthritis

Chikungunya virus, once confined to the Eastern Hemisphere; has infected more than 1 million people in the Americas since 2013 when mosquitoes carrying the virus discovered in the Caribbean. Most people who become infected develop a fever and joint pain that last about a week. But in up to half of patients; the virus can…

Macrophages

Novel Therapeutic Strategy For Rheumatoid Arthritis

A collaborative study has identified a new molecular mechanism causing rheumatoid arthritis. The researchers found that the death of macrophages, an immune cell type, can trigger the disease. Moreover, they discovered how the protein A20 prevents macrophage death and protects against arthritis. These findings open up new possibilities for the treatment of this debilitating disease.…

Macrophages

New Molecular Mechanism Causing Rheumatoid Arthritis

Rheumatoid arthritis (RA) is an autoimmune disease in which the body’s immune system which normally protects its health by attacking foreign substances; like bacteria and viruses mistakenly attacks the joints. This creates inflammation that causes the tissue that lines the inside of joints to thicken; resulting in swelling and pain in and around the joints.…

Arthritis Drugs

Impact Of Arthritis Drugs On Gene Expression

In an era of unprecedented accumulation of biomedical data; our understanding of the mechanisms of the development of complex diseases is greatly by the performance of high-throughput; experiments and their subsequent analyses at various levels that range from single genes to biological pathways, modules, and networks. Genome-wide transcriptomic profiling has instrumental in providing accurate representations…

Rheumatologic Disease

Wearables Are Using By Patients With Rheumatologic Disease

Rheumatism or rheumatic disorder is an umbrella term for conditions causing chronic; often intermittent pain affecting the joints and/or connective tissue. The study of, and therapeutic interventions in, such disorders is rheumatology. The term “rheumatism”, however, does not designate any specific disorder but covers at least 200 different conditions. Sources dealing with rheumatism tend to focus on…

Physical inactivity

Physical Inactivity Among Adults With Arthritis

Approximately one in four U.S. adults have arthritis. Severe joint pain and physical inactivity are common among adults with arthritis and are to poor mental and physical health outcomes. In 2017, marked state-specific variations in prevalences of arthritis, severe joint pain; physical inactivity was observed. Physical inactivity was more prevalent among persons with severe joint…

Japanese Rheumatoid

Shared Decision-Making: In Japanese Rheumatoid Arthritis Patients

Since the 1990s, shared decision-making (SDM) as a component of personalized patient care; has attracted a great deal of interest, in particular in North America and Europe. The introduction of informed consent rules, new demands regarding consumer advocacy and informed choice, “doctor shopping,” and advances in treatment options have together led to the transition of…

Functional disability

Rheumatoid Arthritis: Affected By Functional Disability

Patients diagnosed with rheumatoid arthritis often are affected by functional disability a year or two before the disease is diagnosed; according to new Mayo Clinic research. The results of the study, suggest that daily activities such as eating, dressing, and walking are affected early in the course of the disease and that most rheumatoid arthritis…

ACL Injury

ACL Injury Typically Affects Active Young Adults

A tear of the anterior cruciate ligament in a knee is not just painful; at the moment the injury also increases a patient’s risk of developing osteoarthritis later. The team uses magnetic resonance imaging (MRI) test results; finite element models, gait analysis and biochemical analysis to study ACL injuries; determine which stresses on cartilage may…