All news from Rheumatology

Obesity with Osteoarthritis

Drug Shows To Treat Diet-Induced Osteoarthritis

Metabolic osteoarthritis (OA) is a newly phenotype of OA, which is associated with metabolic syndrome (MetS) and obesity. The main pathophysiologic mechanism underlying obesity-associated osteoarthritis is perpetual inflammation, resulting in cartilage loss; osteophyte formation, and synovitis that lead to the development of OA. The researcher recently demonstrated that rats fed with a high-carbohydrate high-fat diet…

Osteoarthritis

Long-Term Opioid Use In Patients With Severe Osteoarthritis

Osteoarthritis (OA) is a type of joint disease that results from the breakdown of joint cartilage and underlying bone. The most common symptoms are joint pain and stiffness. Initially, symptoms may occur only following exercise, but over time may become constant. Other symptoms may include joint swelling, decreased range of motion, and, when the back is affected, weakness or numbness of the arms and legs. The most commonly…

Arthritis

The Way For New genetic Cause Of Arthritis

Identical twin toddlers who presented with severe arthritis helped scientists to identify the first gene mutation that can single-handedly cause a juvenile form of this inflammatory joint disease.  By investigating the DNA of individual blood cells of both children and then modeling the genetic defect; the research team led by Adrian Liston (VIB-KU Leuven) was…

osteoarthritis

LDL Cholesterol May Be Linked To Risk For Osteoarthritis

Recent data published in Arthritis & Rheumatology provide evidence of a causal role of lower low-density lipoprotein cholesterol (LDL-C) and higher body mass index (BMI) in osteoarthritis (OA). Knee osteoarthritis (RKOA) is associates with an increased risk of mortality from cardiovascular disease (CVD), diabetes, and renal diseases. But self-reported OA is not, according to a study published in the December…

LDL Cholesterol, BMI May Be Linked To Risk For Osteoarthritis

Osteoarthritis  (OA) is a type of joint disease that results from the breakdown of joint cartilage and underlying bone. The common symptoms are joint pain and stiffness symptoms may occur only following exercise, Hence time may become constant. Joint Swelling Meanwhile Other symptoms may include joint swelling, decreased range of motion, and, it affects the back, weakness or numbness of the arms and legs.…

Proteins Influences The Advancement Of Osteoarthritis

A network of carbohydrate binding proteins so-called galectins plays an important role in the degeneration of cartilage in osteoarthritis. A research group at the MedUni Vienna was able to demonstrate this correlation, in cooperation with international study partners. In osteoarthritis, certain galectins are produced by the cartilage cells themselves and accelerate the degeneration process of the cartilage matrix.

Fish Intake May Not Protect Against Rheumatoid Arthritis

Dietary intake of fish or marine omega-3 fatty acids does not have a protective effect against rheumatoid arthritis (RA), according to results published in BMC Musculoskeletal Disorders. Furthermore, the results indicated that fish intake reduced the strong association between smoking and RA diagnosed in patients younger than 55 years, but this association requires further study.