Radiation therapy

The researchers and clinicians has agreed that light therapy is among the most effective interventions for the prevention of oral mucositis, painful ulcers in the mouth resulting from cancer therapy. Therefore The new guidelines from the Multinational Association of Supportive Care in Cancer (MASCC) and International Society of Oral Oncology (ISOO); but  present a significant upgrade in care guidelines for adult cancer patients worldwide. Because The guidelines recommend photobiomodulation therapy; a form of low-dose light therapy; for the prevention of oral mucositis caused by radiation therapy for head and neck cancer or stem cell transplantation.

Caused by radiation therapy

“Many cancer patients can now benefit from this treatment; said Praveen Arany, DDS, Ph.D., co-corresponding author on the paper and assistant professor of oral biology at the University at Buffalo School of Dental Medicine. “The staggering breadth of clinical application for photobiomodulation therapy has been both a boon and a bane for the field. Several anecdotal clinical reports have been plagued with inconsistent outcomes and questionable rationales; often relegating this treatment to a pseudoscience.”

Arany also said recent advancements are enabling rigorous validation of clinical protocols. “This is a major milestone for the field and we are confident it will set a clear path for several exciting clinical applications for photo biomodulation therapy from concussions and wound healing to exciting new work with regenerative medicine and stem cells;” said Arany, who is president of the World Association for photobiomoduLation Therapy (WALT).

Exciting clinical applications

Multiple studies have found that patients report oral mucositis as the worst side effect of their cancer treatment. Pain from the condition can slow or delay cancer treatment; and in severe cases require hospitalization. Light therapies have existed for decades, but improvements in the technology have made the treatment more affordable for wider use. At a high power, light, often in the form of a laser; is used in medicine to cut or destroy tissue.

But at a low power, it has the ability to relieve pain or inflammation and promote healing.The treatment is rising in use across Europe, Brazil, India, Canada and several other nations. therefore The findings provide an upgrade to previous guidelines published in 2013, which noted the effectiveness of light therapy and recommended, based on relatively limited evidence at that time, the intervention as an optional therapy in specific cancer patient populations and settings.

Effectiveness of light therapy

“These updated guidelines will provide health care professionals with better tools to deliver care for cancer patients, said Elad, also professor at Eastman Institute for Oral Health at the University of Rochester Medical Center. “But even with the best evidence-based interventions, we don’t yet have an ultimate guideline for mucositis in all clinical settings.