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Animal Intelligence

Rewards Might Mask Animal Intelligence

Rewards are frequently used to promote Animal Intelligence; but rewards may actually mask true knowledge; finds a new Johns Hopkins University study with rodents and ferrets. The findings, published May 14 in Nature Communications, show a distinction between knowledge and performance, and provide insight into how environment can affect the two. “Most learning research focuses…

Telomeres

Direct Oxidative Stress Damage Might Shorten Telomeres

The same sources thought to inflict oxidative stress on cells—pollution, diesel exhaust, smoking and obesity; also are associating with shorter telomeres, the protective tips on the ends of the chromosomal shoelace. A new study from the University of Pittsburgh, published today in Molecular Cell, provides the first smoking gun evidence that oxidative stress; acts directly…

KRAS Mutation

Conquering Cancer’s Infamous KRAS Mutation

KRAS is one of the most challenging targets in cancer. Despite its discovery more than 60 years, researchers still struggle to inhibit; but its mutated form—earning its reputation as “undruggable.” Yet, the hunt for an Achilles’ heel continues, as cancers driven; by KRAS mutations are both common and deadly. Now, scientists from Sanford Burnham Prebys…

Ischemic Stroke

Adrenergic Receptor Facilitates Recovery From Acute Ischemic Stroke

New research shows that brain fluids can be normalizing with adrenergic receptor antagonists; a combination of drugs to block the activity of (nor)adrenaline in the brain. This experimental treatment for stroke aided motor recovery; and reduced cell death in mice, as reported in the Proceedings of the National Academy of Sciences on May 13. Brain…

Physiological Reactions

Rats Have Similar Physiological Reactions As Humans

Rats have similar physiological reactions to humans when it comes to sex, and perhaps also to orgasm. In fact, a good deal of what we know about what happens; in our brains during orgasm comes from the laboratory rat. While much of what happens in the brain during human orgasm remains a mystery; decades of…

Fibrocytes

Fibrocytes Might Be Used For Regenerative Therapies

A new study by a University of Wisconsin School of Medicine and Public Health researcher shows that someday; fibrocytes may be used for regenerative therapies for people who need to have their vocal folds; or other tissues rebuilt after damage or loss. Nathan Welham, associate professor of surgery; and colleagues published their study of fibrocytes…

R and D

New Molecule Maps Cerebrovascular System

Brazilian and U.S. researchers have developed a molecule called FRW that proved capable of binding to blood vessels in the brain but not in other organs when injected into the bloodstream in tests with mice. They used the technique to produce the first ever complete map of the vasculature of the brain; paving the way…

New molecule maps cerebrovascular system

Breakthrough Molecule Tracks Cerebrovascular System

Brazilian and U.S. researchers have developed a molecule called FRW that proved capable of binding to blood vessels; but in the brain but not in other organs when injected into the bloodstream in tests with mice. They used the technique to produce the first ever complete map of the vasculature of the brain;  therefore paving…

Gene Elimination

Gene Elimination Prevents Development Of Pancreatic Cancer In Mice

The action of a gene called ATDC is required for the development of pancreatic cancer, a new study finds. The work builds on the theory that many cancers arise when adult cells; to resupply cells lost to injury and inflammation switch back into more “primitive,” high-growth cell types; like those that drive fetal development. When…

Muscle Regrowth

Injections, Exercise Promote Muscle Regrowth

By injecting cells that support blood vessel growth into muscles depleted by inactivity; but researchers say they are able to help restore muscle mass lost as a result of immobility. The research, conducted in adult mice, involved injections of cells called pericytes (PERRY-sites); but promote blood vessel growth; and dilation in tissues throughout the body.…

Restoring brain function

Restoring Brain Function in Mice with Alzheimer's Disease

A study in mice shows that selectively removing cells; that are no longer dividing from the brains of mice; with a form of Alzheimer’s disease can reduce brain damage and inflammation; and slow the pace of cognitive decline. These findings, say researchers, add to evidence that such senescent cells contribute to the damage caused by…

Mouse studies show minimally invasive route

Mouse Studies Shows Minimally Invasive Route: Drugs to Brain

In experiments in mice, Johns Hopkins researchers say; they have developed a technique that facilitates the precise placement of cancer drugs; at their intended targets in the brain. This approach pairs a technique that guides a catheter; through the brain’s arteries with positron emission technology (PET); scans to precisely place cancer drugs at their intended…