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Insulin Resistance Increase Proportion Of β Cells

Insulin Resistance Increase Proportion Of β Cells

Research study in the mice that insulin resistance increases the proportion of aged β cells which are dysfunction. Such an increase in aged β cells could lead to type 2 diabetes. As type 2 diabetes is an age related disease. Although changes in function and proliferation of aging β cells resemble those preceding the development…

Incurable Mammalian Neuro Degenerative Disorders

Incurable Mammalian Neuro Degenerative Disorders

Infectious proteins like prions that are responsible for a group of related; fatal, and incurable mammalian neuro degenerative disorders, which continue to increase in variety in novel species; which including the bovine spongiform encephalopathy or Mad Cow disease and Creutzfeldt Jakob disease; both of which affect humans. Which is an chronic wasting disease; also causing…

Significant Sex Associated Differences In Animals

Significant Sex Associated Differences In Animals

Research determining and viewing female rodents as research subjects; through the same lens that determine about women in society.This study comprising half males and half females; But however such an approach are not allowing enough statistical power to detect significant sex associated differences; examination of data will allow the observation of potential trends. But in…

Fabricate Nanometer Sized Drug Delivery Vehicles

Fabricate Nanometer Sized Drug Delivery Vehicles

By developing a path to fabricate nanometer sized drug delivery vehicles that can simultaneously deliver multiple drugs more efficiently that current methods. The system suppressed breast tumors in mice by 87 and 94 percent; using very low dosages of drugs that previously were only deliverable orally. The development of multi functional nano vehicles with enhanced…

Clinical Scores In The Remdesivir Treated Animals

Clinical Scores In The Remdesivir Treated Animals

Nipah virus causes severe and often fatal respiratory and neurological disease in humans;Nipah virus was isolated from a throat swab collected; from a patient with Nipah virus disease in Bangladesh . Researchers from CDC and NIH’s National Institute of Allergy and Infectious Diseases (NIAID); collaborated on the concept for the animals study; NIAID and Remdesivir…

Anti-Inflammatory Responses During A Viral Infection

Anti-Inflammatory Responses During A Viral Infection

Herpes simplex encephalitis rarely occurs in conjunction with oral or genital lesions. These existences of certain microorganisms in the gut; may bolster the immune system’s ability to fend off a herpes viral attack that can cause fatal brain inflammation. Herpes simplex infection is an acute viral disease usually spread from person to person; It is…

Brain Activity In Freely Moving Mice

Brain Activity Of Multiple Freely Moving Mice

Brain functions and related psychiatric disorders have been investigated by recording electrophysiological field potentials. Electroencephalography (EEG) measures whole brain wide activity; while local field potential recording detects the dynamics of more localized micro-networks of the neurons. Electrophysiological  field potential dynamics have been widely using to investigate brain functions and related psychiatric disorders. Considering recent demand…

Treatment for Gama-Sarcoglycanopathy

Treatment For Gamma-Sarcoglycanopathy

Gamma-Sarcoglycanopathy (LGMD2C) is one of the most common limb-girdle myopathies. It affects less than 10 people per 1,000,000 and is characterized by progressive muscle weakness in the pelvis (pelvic girdle) and shoulders (scapular girdle), linked to mutations in the SGCG gene encoding gamma-sarcoglycan. There is currently no cure for this neuromuscular disease. Sarcoglycanopathies are rare…

Novel study of joint cartilage

A Novel Study of Joint Cartilage And Space Travel

A novel study of mice aboard a Russian spaceflight may raise an intriguing question for the astronauts of tomorrow. Could traveling in space be bad for your joints? Researchers found early signs of cartilage breakdown in the mice, suggesting that the reduced biomechanical forces of spaceflight are at play on the musculoskeletal system. A novel…

Adrenal Disorders

Women More Likely To Develop Adrenal Disorders

Worldwide Cancer Research, La Ligue Contre le Cancer and the ANR supported this research. The research was published in Cell Stem Cell. Scientists have discovered a potential biological reason why women are more likely to develop adrenal disorders, including cancer. According to the researchers, the answer could lie in the increased turnover; of hormone-producing cells found…

Tumor Removal in dogs

Complete Tumor Removal Reduces Cancer Recurrence In Dogs

The relative risk of a recurrence of cancer is reducing 60% in dogs whose tumors are completely removing; a new analysis by Oregon State University researchers has found. The researchers reviewed published veterinary studies and found a recurrence of less than 10%; but in dogs where the soft tissue sarcoma was completely excising; versus 33%…

Alzheimer's Research

Machine Learning Tool Immensely Scales UIp Alzheimer’s Research

Researchers at UC Davis and UC San Francisco have found a way to teach a computer to precisely detect; one of the hallmarks of Alzheimer’s disease in human brain tissue; delivering a proof of concept for a machine-learning approach to distinguishing critical markers of the disease. Amyloid plaques are clumps of protein fragments in the…