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Benefits Of Novel Vaccine Immunotherapy

Benefits Of Novel Vaccine Immunotherapy

The research trial on a bee sting vaccine containing a novel adjuvant called Advax; to increase its efficacy has raised hopes that severe allergic reactions, sometimes fatal; to bee venom in allergic people could soon be a thing of the past. The vaccine was designing to neutralize the venom of the European honeybee. The research…

Chip Based Method For Drug Development

Chip Based Method For Drug Development

The drug development often relies on high throughput cell basing screening of large compound libraries. In spite of increasing demand, the number of newly developed drugs decreased continuously in the past decades. However, the lack of miniaturized and parallelized methodologies for high-throughput chemical synthesis in the liquid phase and incompatibility of synthesis of bioactive compounds and screening for their…

Lung Stromal Cells Protect From Influenza Virus Infection

Lung Stromal Cells Protect Antibiotic From Influenza Virus Infection

This study supporting that taking antibiotics inappropriately not only promotes antibiotic resistance; and wipes out the commensals in the human gut that are useful and protective; but it may also render you more susceptible to viral infections. In some countries, the livestock industry uses antibiotics a lot, prophylactically, so treated animals may become more susceptible…

Cytomegalovirus Evades Antibody Mediated Immunity

Cytomegalovirus Evades Antibody Mediated Immunity

Human cytomegalovirus (HCMV) can persistently infect humans, but how HCMV avoids humoral immunity is not clear. The neonatal Fc receptor (FcRn) controls IgG transport from the mother to the fetus and prolongs IgG half-life. Once contracting; it lays dormant in your body for the rest of your life; and can flare up whenever your immune…

Remodeling Associated With Hemarthrosis In Factor VIII‐Deficient Mice

Remodeling Associated With Hemarthrosis In Factor VIII‐Deficient Mice

The research study on the remodeling associating with hemarthrosis in factor VIII‐deficient mice. Pathological changes include; synovial inflammation/hypertrophy and cartilage destruction. But recent studies have identifying profound vascular changes associating with joint bleeding that may destablize vessels; thereby contributing to bleeding tendencies and HA progression. Hemarthrosis in FVIII-deficient mice leads to synovial neovascularization and associated…

Subtypes Of Liver Cells In Health And Disease

Subtypes Of Liver Cells In Health And Disease

Liver diseases are one of the biggest health problems in the world and a leading cause of death. In Germany, at least five million patients are suffering from fatty liver disease, liver cancer, or hepatitis. Despite the immense importance of the liver for human health; the diversity of individual liver cells types and the associating…

Bias In Acute Experimental Spinal Cord Injury

Bias In Acute Experimental Spinal Cord Injury

Clinical trials are costly and resource intense. Improving the predictive value of experimental animal model testing will increase the likelihood; that those findings can be more readily translating into therapies that benefit our patients. Evidence of widespread bias in animal SCI experiments; which have set out to test new interventions in order to improve neurological…

New Development Of Nano theranostics system

New Development Of Nano theranostics system

Theranostics is an emerging field of medicine whose name is a combination of “therapeutics” and “diagnostics”. The system uses “harmonic nanoparticles“; a family of metal-oxide nanocrystals with exceptional optical properties; in particular their emission in response to excitation from ultraviolet to infrared light; and their high photostability.  It was this feature that brought HNPs into…

CRISPR Treatments Eliminate HIV-1 In Infected Humanized Mice

CRISPR Treatments Eliminate HIV-1 In Infected Humanized Mice

HIV is a viral infection that leads to AIDS and is fatal in almost all cases. For decades now; researchers have been trying to find a complete cure for this infection that affects 37 million people  across the globe. But the drugs using against HIV at present are all capable of slowing the progression and…

Gene Editing Tool Prevents Hearing Loss In Mice

Gene Editing Tool Prevents Hearing Loss In Mice

A new approach version of the classic CRISPR-Cas9 gene editing system; that is better at recognizing the disease causing mutation seen in Beethoven mice. The refining tool allowing scientists to selectively disable the defective copy of a hearing gene called Tmc1; while sparing the healthy copy. By using novel gene editing approach to salvage the…

Artificial Cells Using Histamine Responsive Synthetic

Artificial Cells Using Histamine Responsive Synthetic

Artificial cells are cell-like compartments that encapsulate reactive components to mimic cellular behaviors such as replication, metabolism, intercellular communication, and environmental adaptation; Synthesizing cells from scratch is of fundamental importance to understand what life is; Nucleic Acid Chemistry and Engineering Unit. The compartments can be chemically analogous to those of biological cells such as phospholipid…

monoamine

Mystical Psychedelic Compound In Normal Brain

As dimethyltryptamine is not just in plants; but also can be detecting in mammals.Drinkers of Ayahuasca experience short term brain hallucinogenic episodes many describing as life changing. The active ingredient responsible for these psychedelic visions is a molecule knowing dimethyltryptamine; as dimethyltryptamine came about accidentally. Before studying the psychedelic; the research focusing on melatonin production…