Healthy cells have a built in self destruct mechanism; Strands of DNA called “telomeres” act as protective caps on the ends of your chromosomes. Each time a cell replicates, telomeres get a little shorter. Think of it like filing your nails with an Emory board after enough filing, you hit your fingertip ouch; In the…
The study finding that burst firings of 35–80 Hz appeared in the culturing SCN slice of fetal mice; and obscured the circadian firing rhythm when GABA signaling was genetically or pharmacologically disrupted. Calcium spikes, which synchronizing with burst firings; were also observing in GABA-deficient SCN. Researchers discover role of GABA neurons in the central circadian clock.…
According to the study, researchers involving and giving monkeys infecting with SIV where the monkey equivalent of HIV; the standard antiviral treatment for HIV study also administering an antibody to target a protein called a4b7; which prior research had suggesting the virus exploits to hide from antibodies. Study showing that the monkeys showed no signs…
According to the study, researchers determining that Zika virus infects the adult human brain; and causes memory deficits in animal models. Zika virus (ZIKV) interferes with the cellular machinery controlling cell division; and alters the expression of hundreds of genes guiding the formation and development of neurons and astrocytes. Zika virus attracted worldwide attention in…
The study focuses on the pre-mRNA splicing process where regions in the pre-mRNA that do not encode proteins are removed by the spliceosome, a huge protein-RNA complex. Remaining sections of the RNA transcript, called exons, are then stuck back together. Pre-mRNA splicing is one of several essential steps that convert pre-mRNAs into mature mRNA (messenger…
The research study showing that the restoring process in a gene altering in Down syndrome; rescues the adult neurogenesis and learning and memory defects in mice. Where the researchers explaining the restoring a gene altered in Down syndrome called the Down syndrome critical region 1 (DSCR1) rescued adult neurogenesis and learning and memory defects in…
According to the study, researchers shed new light on how the brain constructs itself; The cerebral cortex acts as the control center of our cognitive processes. During embryogenesis, dozens of types of neurons with distinct functions come together to form the circuits that drive our thoughts and actions. These neurons are generated by progenitor cells,…
According to the research study, the researchers have describing a new mechanisms; which inducing the self-killing of cancer cells by perturbing ion homeostasis. By this the study developing an helical polypeptide potassium ionophores; that lead to the onset of programmed cell death. The ionophores increase the active oxygen concentration to stress endoplasmic reticulum to the…
The immune system coming ready for battle against bacteria, viruses, fungi and even cancer. But in cases of autoimmune disease; the immune system cells superpowers turn it into a supervillain. But now scientists have discovering a way to stop certain immune system cells from mistakenly attacking the body. Suggesting that a new way to target…
Researchers finding that antibodies; which unlock the body’s regenerative potential. As body making antibodies to fight the infections. But the synthetic versions of these molecules could hold the key to stimulating the body’s ability to regenerate. Antibodies are increasingly being developing into drugs to their ability to bind and affect the function of other proteins…
Research study stating that a novel technology for genome editing; a broad range of mutations in live organisms. The ability to edit genes in living organisms offers the opportunity to treat a plethora of inherited diseases. However, many types of gene-editing tools are unable to target critical areas of DNA, and creating such a technology…
Researchers developing a new study on preventing tumor metastasis; study taking an important step toward the development of an agent against the metastasis of certain cancers. Using the Swiss Light Source, they deciphering the structure of a receptor that plays a crucial role in the migration of cancer cells. This making it possible to identifying…