All news from Pulmonary Medicine

Lung Diseases in Premature Babies: Treatment with Innovative Inhalation System

Premature babies who have born before their lungs have finished maturing often suffer from a lack of surfactant – a necessary substance for lung development. They are also particularly susceptible to illnesses of the respiratory organ, which have to be treated by means of inhalation. However, the inhalation systems available are not geared to the needs of preterm infants and newborns. Researchers are working with partners to develop a system that would allow drugs to be administered as aerosols in an efficient and breath-triggered manner. This would shorten the duration of therapy, so easing the strain on little bodies.

Bacterial Pneumonia Diagnosis With aid of Nanoparticles-Based Technology

MIT researchers have now developed a nanoparticle-based technology that could be used to improve the speed of diagnosis. This type of sensor could also be used to monitor whether antibiotic therapy has successfully treated the infection, says Sangeeta Bhatia, the John and Dorothy Wilson Professor of Health Sciences and Technology and Electrical Engineering and Computer Science and the senior author of the study.

Study Warns: Proposed Cancer Treatment Boost Lung Cancer Stem Cells

Epigenetic therapies—targeting enzymes that alter what genes are turned on or off in a cell—are of growing interest in the cancer field as a way of making cancer less aggressive or less malignant.

Researchers at Boston Children's Hospital now report that at least one epigenetic therapy that initially looked promising for lung cancer actually has the opposite effect, boosting cancer stem cells that are believed to drive tumors. They also identify a strategy that reduces these cells, curbing lung cancer in mice. Findings were published online today in Nature Communications.