Lung cancer is the most common cancer worldwide and the most common cause of cancer deaths. In Australia, there will an estimated 12 741 new cases and 9198 deaths due to lung cancer in 2018. Although there have been recent improvements in outcomes for lung cancer; 5-year survival in Australia is only 16% and less than 10% in…
In a new article published in Tissue Engineering, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers; researchers report the development of a high-throughput, automated; multichannel lung bioreactor that allows a parallel culture of up to five human cell-populated isolated rat lung scaffolds. Manufactured or Engineered Device The bioreactor may refer to any manufactured or engineered device or system that supports a biologically active…
Researchers have long known that fibrosis scarred tissue and organs is caused by a wound healing mechanism that goes awry beyond normal wound repair. Fibrosis of the lung, or pulmonary fibrosis; is a deadly condition in which the tissues of the lungs thicken and harden; and eventually, stop functioning. Survival rates are low: Without a lung transplant; most…
After treatment for lung cancer, web-based monitoring of patient-reported outcomes is associated with improved overall survival, according to final results from a randomized trial. "Electronic patient-reported symptom monitoring should be considered for patients with lung cancer who have received treatment as a part of high-quality cancer care," Dr. Fabrice Denis from Institut Inter-regional de Cancerologie Jean-Bernard, Le Mans, France told Reuters Health.
A new study published in the January issue of CHEST establishes that patients with chronic obstructive pulmonary disease (COPD) face heightened risks of death, critical illness, and hospitalization if they develop the flu and demonstrates the beneficial effects of influenza vaccination.
Inappropriate prescribing of antibiotics for children with acute bronchiolitis persists in U.S. emergency departments (EDs), researchers report. Bronchiolitis is a viral infection which does not respond to or requires antibiotic treatment, and guidelines of the American Academy of Pediatrics (AAP), first published in 2006, recommend against the use of antibiotics for this illness," said Dr. Brett Burstein from McGill University Health Center, in Montreal, Canada.
A £2.68 million study to investigate the effective use of antibiotics to treat certain types of severe asthma is being spearheaded by researchers in Leicester. The project, which is chiefly funded by a partnership between the National Institute for Health Research (NIHR) and Medical Research Council (MRC), is part designed by asthma patients working with Asthma UK.
A new vaccine candidate shows promise for prevention active pulmonary tuberculosis (TB) in adults infected with Mycobacterium tuberculosis. The vaccine, M72 / AS01E, provided 54% protection against active pulmonary TB.
As levels of ozone and fine particulate pollution (PM2.5) rise, more patients end up in the ER with breathing problems, according to the largest U.S. study of air pollution and respiratory emergency room visits of patients of all ages. The study was published online in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine.
Lung cancer remains a major cause of mortality across the globe, although we are gaining a deeper understanding of the genetic background behind this disease, including the mutations that promote it. Mutation in the gene EGFR is known to be a particular risk factor for developing lung cancer and for the emergence of resistance to otherwise effective treatments, but the mechanism behind this has remained unclear.
Researchers at Osaka University have identified a protein that is involved in treatment resistance in lung cancer cells carrying a common cancer-related mutation , which could be used for predicting prognosis or treating these patients.
Compared with idiopathic pulmonary fibrosis (IPF), nonhoneycomb hypersensitivity pneumonitis (HP) phenotypes are associated with longer survival and greater improvements in percent-predicted forced vital capacity (FVC%), according to a study published in CHEST .