All news from Psychiatry

Doubly Randomized Preference Trial of Prolonged Exposure Versus Sertraline for Treatment of PTSD

A multiyear clinical trial comparing medication and mental health in the treatment of post-traumatic stress disorder shows that patients who chose their form of treatment-whether drugs or therapy improved more than those who were simply prescribed one or the other regardless of the patient's preference. The study was published in the  American Journal of Psychiatry.

This is the first large-scale trial of hundreds of PTSD patients, including veterans and survivors of sexual assault, to measure if a patient preference in the course of treatment with the effectiveness of a type of cognitive behavioral therapy and use of selective serotonin reuptake inhibitors, a type of antidepressant often prescribed for PTSD.

Human Neuronal Differentiation For Functional Investigation of Schizophrenia Polygenic Risk

Researchers examined the process in which new neurons were designated for certain roles, and found that changes in gene expression over the course of neural development were significantly associated with genetic risk for schizophrenia.

They have established a new analytical method for investigating the complex genetic origins of mental illnesses using brain cells that are grown in a dish from human embryonic stem cells. The study was published in Biological Psychiatry. 

Differences In Brain Structure Among Patients With Schizophrenia

Schizophrenia is an extremely variable psychiatric disorder that is diagnosed based on the presence of specific symptoms. Thomas Wolfers and André Marquand of Radboud university medical center investigated how much the brains of individual patients diagnosed with schizophrenia differ from the 'average' patient.

For this purpose, they compared brain scans of 250 healthy individuals with those of 218 individuals with schizophrenia. Those with schizophrenia as a group differed from the healthy individuals in frontal brain regions, the cerebellum, and the temporal cortex. The study was published in JAMA Psychiatry.

Mental Health Conditions Can Harm More Than Good

The number of people diagnosed with a mental health condition is increasing, globally. Diagnostic labels can act as passports to accessing public services and help create communities of individuals with the same label. But are these reasons enough to justify their continued use? Getting a diagnostic label is no guarantee of getting the right treatment, and it is often associated with worry and stigma.

Sentence Reduction Affected By Mental Illness

Just last week, the Victorian Court of Appeal significantly reduced the sentence given to Akon Guide, a mother who killed three of her children after driving her car into a lake in Melbourne. The main reason for the 8½ year sentence reduction was that the trial judge had not sufficiently taken Guide's major depression into account.

On-Off Relationships Are Toxic For Mental Health

These are just some of the notable on-again, off-again couples found in pop culture. While their relationships made for storylines that kept viewers entertained, a researcher from the University of Missouri says that the pattern of breaking up and getting back together can impact an individual's mental health and not for the better. He suggests people in these kinds of relationships should make informed decisions about stabilizing or safely terminating their relationships.

Mortality In The US From Self-Injury Surpasses Diabetes

Researchers examined the self-injury mortality(SIM), a composite of all methods of suicide and estimated non-suicide deaths from drug self-intoxication, has surpassed diabetes as the seventh leading cause of death in the United States, prompting researchers to call for a new unified approach to SIM prevention.

It is time to end the siloed approach to prevention. Mortality in the United States from self-injury surpasses diabetes: a prevention imperative. The study was published online by Injury Prevention. They are so entrenched in separating suicide from a drug overdose or alcohol poisoning deaths that people can't wrap their heads around the idea that they are related.