All news from Physiology

Chronic Inflammatory Diseases

Unique Approach To Treat Some Chronic Inflammatory Diseases

Inflammation is a balanced physiological response the body needs it to eliminate invasive organisms and foreign irritants; but excessive inflammation can harm healthy cells, contributing to aging and chronic diseases. To help keep tabs on inflammation, immune cells employ a molecular machine called the NLRP3 inflammasome. NLRP3 is inactive in a healthy cell, but is…

Sleepless night

Negative Impressions : A Sleep-Deprived Brain Interprets

A sleepless night not only leaves us fatigued and distracted, but it also makes us interpret things more negatively and makes us more likely to lose our temper. Moreover, people suffering from a pollen allergy are at high risk of some form of sleep disruption from the outset. This according to a new doctoral thesis…

Sleep Disruption

Sleep Disruption Leads To Negativity Bias

A sleepless night not only leaves us fatigued and distracted; but it also makes us interpret things more negatively and makes us more likely to lose our temper. Moreover, people suffering from a pollen allergy are at high risk of some form of sleep disruption from the outset. This according to a new doctoral thesis…

Sleepiness

Sleepiness And Cardiometabolic Risk Factors

A new study appearing in the journal CHEST may change the way we think about sleep disorders. In this study led by Dr. Luciano F. Drager, obstructive sleep apnea (OSA) and short sleep duration (SSD); compared with excessive daytime sleepiness; anxiety/depressive symptoms; and several cardiometabolic risk factors including obesity, hypertension, diabetes, and dyslipidemia. Using a large…

Sleeping At Work

Sleeping At Work: You Should Be Fired

In days gone by, when our economy was dominated by agriculture and manufacturing; an employee’s value was gauged by their inputs. If they slacked off by not placing a bumper on a car fast enough they were unproductive, and if they slept on the job they stealing time from their employers and could fire. Today,…

Shift Work

Shift Work: Long-Term Effect On Heart Disease And Diabetes Risk

Cardiovascular disease (CVD) is a class of diseases that involve the heart or blood vessels. CVD includes coronary artery diseases (CAD) such as angina and myocardial infarction. Other CVDs include stroke, heart failure, hypertensive heart disease, rheumatic heart disease, cardiomyopathy, heart arrhythmia, congenital heart disease, valvular heart disease, carditis, aortic aneurysms, peripheral artery disease, thromboembolic disease, and venous thrombosis. Diabetes mellitus (DM), commonly known as diabetes; is a group of metabolic disorders by high blood sugar levels over…

Neighbourhood Stressors

Neighbourhood Stressors Are Associated With Telomere Length

Living in a stressful neighborhood is related to aging faster, according to new research using telomeres as a marker for biological aging. Telomeres are part of people’s DNA which give a measure of ‘miles on the clock,” or biological age. The study, published today in PLoS One, combined population health, and molecular biology research and…

Intestinal stem cells

Increase Population Of Intestinal Stem Cells

Cells that line the intestinal tract are replaced every few days; a high rate of turnover that relies on a healthy population of intestinal stem cells. Biologists have now found that aging takes a toll on intestinal stem cells and may contribute to increased susceptibility to disorders of the gastrointestinal tract. The researchers also showed…

Sleep Disorders

Traditional Thinking About Sleep Disorders

Using a large sample of adults, investigators found that SSD, but not OSA; was independent with daytime sleepiness. In contrast, OSA, but not SSD, was independent of obesity, hypertension, and dyslipidemia. Neither was independent of anxiety or depression. Tracking OSA and SSD in the same investigation allowed researchers to compare the potential consequences of the…

Sleep apnoea

Detecting Risk Of Sleep Apnoea

A 3-D scan of your face could all it takes to detect your risk of sleep apnoea. Being woken up by someone snoring can pretty frustrating. Whether it’s from a friend or a loved one; interrupted sleep can leave the best of us feeling tired and cranky. But what if that person stops breathing for…

CAR-T cell therapy

Heating Tumors During CAR T-Cell Therapy

CAR-T cell therapy uses T cells engineered with CARs for cancer therapy. The premise of CAR-T immunotherapy is to modify T cells to recognize cancer cells; in order to more effectively target and destroy them. Scientists harvest T cells from people, genetically alter them; then infuse the resulting CAR-T cells into patients to attack their…

Sleep deprivation

Does Sleep Deprivation Promote Medical Malpractice

Sleep deprivation, also known as insufficient sleep, is the condition of not having enough sleep. It can either chronic or acute and may vary widely in severity. A chronic sleep-restricted state can cause fatigue, daytime sleepiness, clumsiness, and weight loss or weight gain. It adversely affects the brain and cognitive function. However, in a subset of cases…