Micropores in fabricated tissues such as bone and cartilage allow nutrient and oxygen diffusion into the core, and this novel approach may eventually allow lab-grown tissue to contain blood vessels, according to a team of Penn State researchers.
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Scientists of the Higher School of Economics, Indiana University, and École Normale supérieure clarified how alcohol influences the dopamine and inhibitory cells in the midbrain that are involved in the reward system and the formation of dependency on addictive drugs.
A new drug could significantly slow the progression of ALS, also known as Lou Gehrig's disease, according to new research by University of Alberta biologists. Current treatments slow progression of the degenerative disease by only a few months and these findings could revolutionize the treatment of patients suffering from ALS, extending and improving quality of life.
USC scientists report that a novel time-keeping mechanism within liver cells that helps sustain key organ tasks can contribute to diseases when its natural rhythm is disrupted. This dual function of the nuclear receptor protein HNF4A offers a potential explanation for diseases such as diabetes and cancers. It also helps explain why such maladies are more common for people living with disrupted sleep, including night-shift workers, urban dwellers, and international jet-setters.
When Seattle Public Schools announced that it would reorganize school start times across the district for the fall of 2016, the massive undertaking took more than a year to deploy. Elementary schools started earlier, while most middle and all of the district's 18 high schools shifted their opening bell almost an hour later—from 7:50 a.m. to 8:45 a.m.
The neurodegenerative disease ALS causes motor neuron death and paralysis. However, long before the cells die, they lose contact with the muscles as their axons atrophy. Researchers at Karolinska Institutet have now devised a new method that radically improves the ability to study axons and thus to better understand the pathological development of ALS. The method is described in the scientific journal Stem Cell Reports.
Takayasu arteritis is a disease that mainly affects female Asians at a relatively young age. It involves chronic inflammation of the aorta, and potentially leads to fatal disruption of the structures through which blood flows from the heart.
Almost everyone has something they fear maybe it is spiders, enclosed spaces, or heights. When we encounter these "threats," our hearts might begin to race, or our hands may become sweaty. This is called a threat fear response, and it exists to help us avoid potential pain.
Cerebrospinal venous anatomy and hemodynamics changes are associated with many central nervous system disorders. The aim of this study was to detect whether perihematomal edema (PHE) after spontaneous intracerebral hemorrhage (sICH) is associated with cerebral venous outflow volume (CVFV) in the internal jugular veins and vertebral veins.
Developing a new drug often takes years and costs hundreds of millions of dollars. A shortcut has now been reported in a study led by City University of Hong Kong (CityU), which can potentially reduce the time and costs of developing new drugs by sorting out the high potential candidates from a long list of chemical compounds
Researchers from the UCLA Jonsson Comprehensive Cancer Center and the La Jolla Institute for Immunology have identified a new type of T cell called a phospholipid-reactive T cell that is able to recognize phospholipids, the molecules that help form cells' outer membranes
In the hours and days following a spinal cord injury, the gears that control the body's internal clocks fall profoundly out of sync, impacting body temperature, hormone fluctuation, immunity and the timing of a host of other bodily processes, according to new University of Colorado Boulder research