Aerobic Exercise; As obesity increases in aging Western populations, frailty which is exacerbated by obesity is becoming a greater health concern and a major healthcare cost. Now, researchers report July 3 in the journal Cell Metabolism that combining aerobic exercise and resistance training helps elderly obese individuals preserve muscle mass and reverse frailty as they work to lose weight.
Base on a small clinical trial, the study show that patients; who complete these exercises had increase muscle protein synthesis and preserve muscle quality compare to control groups. In a previous study, Dennis T. Villareal, professor and geriatric endocrinologist at Baylor College of Medicine; hence hypothesized that resistance training would best complement weight loss for improving physical function in older obese adults.
The Aerobic Exercise
Villareal and colleagues were surprise to find that combine aerobic; also resistance training improve cardiovascular fitness to the same; so extent as aerobic training alone and improve muscle strength to the same extent; hence as resistance training alone. They report in the New England Journal of Medicine in May 2017 that combine aerobic; also resistance training result in the greatest improvement in physical function and reducing frailty in older obese.
However, it was unclear how obese older adults in particular benefit; so from aerobic workouts geare toward cardiovascular fitness combined resistance training. In the Cell Metabolismstudy, the researchers use molecular and cellular techniques; so to assess changes in their muscle protein synthesis; also myocellular quality to examine the mechanisms underlying the obese older adults; so improvement in physical function and preservation of lean body mass.
A subset of participants 47 of the original 160 agree to undergo muscle biopsies before and after six months of lifestyle interventions to see how their muscle tissue was affected. The participants were men and women that averaged between 69 and 72 years of age and more than half were Hispanic/Latinx.
Negative energy balance
Aerobic activities included treadmill walking, stationary cycling, and stair climbing, with participants exercising at approximately 65% of their peak heart rate; resistance training consist of 1 to 3 sets of 8 to 12 reps on nine upper-body and lower-body weight-lifting machines. Our findings indicate that despite negative energy balance from diet induce weight loss, exercise training in older adults with obesity helps to preserve muscle mass, improve physical function and reduce frailty,” Villareal says.
The study found that the participants’ muscle protein synthesis rate increase; so more with resistance training and combine aerobic-resistance exercise than in the control group. The combine aerobic-resistance exercise was also associate with lower expression of genes associate with muscle atrophy; also the best preservation of muscle growth regulators; which the researchers hypothesized could also play a role in promoting muscle mass preservation and improvement in physical function in that group.
In the elderly obese, combined aerobic and resistance exercise is superior to either mode independently for maintaining muscle mass during weight-loss therapy, he says. Aerobic and resistance training is the most effective strategy and therefore, Villareal notes, “the best approach.”