All news from Pharmacology and Therapeutics

Pharmacology

Breast Cancer Cells Creates New Option for Treatment

Researchers at the University of Zurich and from IBM Research have investigated the varying composition of cancer and immune cells in over 100 breast tumors. They’ve find that aggressive tumors are often dominate by a single type of tumor cell. If certain immune cells are present as well, an immune therapy could be successful for…

Pharmacology

Researchers Study Cost-Effectiveness of Rectal Cancer Treatments

Costs are on the rise for many kinds of medical treatments. UCLA researchers are looking for cost-effective ways to treat people who have locally advanced rectal cancer, a cancer located in the end section of the large intestine. Because “There is a pressing need for cost-effectiveness studies within the field of radiation oncology,” said Dr.…

Pharmacology

Pibrentasvir is Effective in Individuals With Hepatitis C

Two large ‘real-world’ studies conducted in Germany and the USA have confirmed the high rates of sustained virological response (SVR) observed in controlled clinical studies of glecaprevir/pibrentasvir (G/P) involving individuals with hepatitis C virus (HCV) infection. Across the two studies, which are present today at The International Liver Congress 2019 in Vienna. Controlled clinical studies…

Pharmacology

Antibiotics Legitimately Available for Throat Medications

Certain OTC products aimed at treating sore throats contain topical antibiotics, and medications of this type are widely available around the world, including in the UK and many other European countries. This study; commissioned by Adrian Shephard of Reckitt Benckiser Healthcare Ltd; is conduct by researchers from the School of Pharmacy and Pharmaceutical Sciences at Cardiff University; UK…

Pharmacology

Non Antibiotic Strategy for the Treatment of Bacterial Meningitis

Our immune system has several important defenders to call on when an infection affects the central nervous system. The researchers have mapped what happens when one of them, the white blood cells called neutrophils, intervene in bacterial meningitis. If there is an infection, the neutrophils deploy to the infected area in order to capture and…

Pharmacology

Cancer Drug Shortages Have Little Effect on Chemotherapy

Despite chronic shortages of cancer drugs that could disrupt care, a new study has found that to have little impact on outpatient chemotherapy treatment over a seven year period. “These findings are surprising in light of the substantial media and policy attention that the cancer drug shortage problem has garnered,” said Mireille Jacobson, a health economist…

Pharmacology

Anti-Inflammatory Medicine Effective In Treating People

The World Health Organization (WHO) calls depression one of the most serious mental disorders, and researchers around the world are trying to improve treatment of the disease. Now in the largest meta-analysis ever carried out, researchers from iPSYCH have shown that medicine which inhibits inflammation such as e.g. arthritis medicine can also be effective in…

Pharmacology

Experimental Drug Shows Promise for Opioid Withdrawal Symptoms

While medicines are available to relieve withdrawal symptoms in people recovering from opioid addiction, they cause side effects and can maintain the brain changes that led to addiction in the first place, which can lead to relapse before treatment is completed. New research offers hope that a better solution may be on the horizon. Rapastinel,…

Pharmacology

Therapy Clears HPV in one-Third of Cervical Cancer Precursors

The shot, a therapeutic vaccine, injects a specific protein that triggers an immune system response to attack high-risk HPV types that cause nearly all cervical cancer precursors, known as cervical intraepithelial neoplasia, or CIN. “There are very few products trying to cure women who already have an HPV infection;” says Diane Harper, M.D., M.P.H., M.S.,…

Pharmacology

Targeting Triple Negative Breast Cancer with New Drug Design

The type of breast cancer most likely to affect young people and African Americans is also one of the most aggressive and difficult to treat. Triple-negative breast cancer, which represents about 20% of all breast cancer cases, is named for its lack of three common hormone receptors. Since targeted breast cancer treatments typically involve blocking those…

Pharmacology

Researchers Develop 'Nano Vehicle' To Deliver Life-Saving Drugs

Despite many successes, modern medicine is still struggling to find effective treatments for serious pathologies such as cancer and neurodegenerative and inflammatory diseases. For Alzheimer’s disease, for example, only 30% of patients respond to therapy whereas for cancers the figure is only 25%. ‘The real bottleneck is not the absence of an efficient drug but…

Pharmacology

Gabapentin and Pregabalin Become Class C Drugs

An expert in mental health and addiction at the University of York comments on the Government’s move to make gabapentin and pregabalin a class C drug. Ian Hamilton; from the University of York’s Department of Health Sciences; said: “From today (Monday, 1st of April); gabapentin and pregabalin will become class C drugs in a move that…