All news from Pharmacology and Therapeutics

Pharmacology

3 Year Old Son After Discontinuing Chemotherapy

Two Florida parents have lost custody of their young son and could face neglect charges over their decision to discontinue the child’s potentially life-saving cancer treatment.  Three-year-old Noah McAdams was diagnosed with acute lymphoblastic leukemia in early April and struggled through chemotherapy, according to his mother. Acute lymphoblastic leukemia “He had vicious mood swings making…

Pharmacology

Effectiveness of Cancer Treatment by Predicting Gene Interactions

While network algorithms are usually associated with finding friends on social media, researchers at the University of Sussex have shown how they could also be used improve the effectiveness of cancer treatment; by predicting the interactions between genes. There are over 12 million newly diagnosed cases of cancer globally each year and this figure only continues…

Pharmacology

Most Effective Treatment for Women With Breast Cancer

The test was successful in predicting whether chemotherapy would be beneficial for patients with the most common type of breast cancer (oestrogen-receptor positive; HER2-negative), thereby helping to direct patients with a high-risk of metastasis to chemotherapy, while allowing lower-risk patients to opt out of the treatment and its potential side effects. Approximately 85%t of breast…

Pharmacology

FDA Approves New Treatment for Children With Lupus

The U.S. Food and Drug Administration today approved Benlysta (belimumab) intravenous (IV)  of children with systemic lupus erythematosus (SLE) often referred to as simply “lupus” a serious chronic disease that causes inflammation and damage to various body tissues and organs. This is the first time that the FDA has approved a treatment for pediatric patients…

Pharmacology

Potential Drug to Treat Type 2 Diabetes in Children Announced

Results of a recently completed clinical trial of a potential drug to treat Type 2 diabetes in children were announced Sunday  at the Pediatric Academic Societies 2019 meeting in Baltimore, Md. The New England Journal of Medicine also published the findings. Study coauthor Jane Lynch, M.D., FAAP, professor of pediatrics at UT Health San Antonio, said…

Pharmacology

FDA Approves New Treatment for Children With Lupus

The U.S. Food and Drug Administration today approved Benlysta (belimumab) intravenous (IV) infusion for treatment of children with systemic lupus erythematosus (SLE) often referred to as simply “lupus” a serious chronic disease that causes inflammation and damage to various body tissues and organs. This is the first time that the FDA has approved a treatment…

Pharmacology

Predicting Whether a Patient Will Benefit From Chemotherapy

Case Western Reserve University researchers and partners, including a collaborator at Cleveland Clinic, are pushing the boundaries of how “smart” diagnostic-imaging machines identify cancers and uncovering clues outside the tumor to tell whether a patient will respond well to chemotherapy. The recent findings in breast and lung cancer research build off work pioneered by biomedical…

Pharmacology

Perspectives on Pharmacotherapy to Treat Alcohol Use Disorder

Alcohol use disorders (AUDs) cause nearly 90,000 deaths a year in the United States, making them the third leading cause of preventable death. Rates of AUD are particularly high among military personnel. According to the 2015 Department of Defense Health Related Behaviors Survey, 35% of service personnel met criteria indicative of hazardous drinking or a…

Curcumin

Possible Therapeutic Effects Of Curcumin On Stomach Cancer

Curcumin is widely used to impart color and flavor to food, but scientists have discovered that this yellow powder derived from the roots of the turmeric plant (Curcuma longa) can also help prevent or combat stomach cancer. The study by researchers at the Federal University of São Paulo (UNIFESP); and the Federal University of Pará…

pharmacology

Researchers Are Developing New Method to Cure Brain Tumors

Scientists from Far Eastern Federal University (FEFU) in cooperation with colleagues from Blokhin Russian Cancer Research Center (Moscow), Switzerland, and Sweden for the first time studied proteins, which constitute WNT signaling pathway of the cancer stem cells of glioblastoma multiforme (GBM CD133+ CSCs), one of the most aggressive brain tumors.  Researchers revealed a number of…

Pharmacology

New Way For Treatment of Necrotizing Enterocolitis

Cutting-edge discovery in the lab of Catherine Hunter, MD, from Stanley Manne Children’s Research Institute at Ann & Robert H. Lurie Children’s Hospital of Chicago offers a new direction toward treatment of necrotizing enterocolitis (NEC)  a devastating intestinal emergency that occurs in up to 10% of premature infants. NEC is a leading cause of overall…

Pharmacology

Unique Partnership to Deliver Cancer Treatments

Scientists at Christiana Care Health System’s Gene Editing Institute and NovellusDx, an Israeli biotechnology company, have deployed a breakthrough CRISPR gene-editing tool to successfully engineer multiple edits simultaneously to fragments of DNA extracted from a human cell, according to a new study published today in The CRISPR Journal. The tool can rapidly reproduce; in a human…