All news from Pharmacology and Therapeutics

Pharmacology

New Organic Molecule Fight Against Antibiotic Resistance

The researches find that the An organic molecule composed of simple sugars could become a potent weapon in the fight against rising antibiotic resistance, according to EU-funded researchers who have developed a novel, targeted drug-delivery technique to treat deadly tuberculosis and other lethal pathogens. The EU-funded CYCLON HIT project investigated cyclodextrins cyclic oligosaccharides whose molecular…

Pharmacology

New Drug Delivery System Disguises Chemotherapeutics

A stealthy new drug-delivery system disguises chemotherapeutic as fat in order to outsmart, penetrate and destroy tumors. Thinking the drugs are tasty fats, tumors invite the drug inside. Once there, the targeted drug activates, immediately suppressing tumor growth. The drug also is lower in toxicity than current chemotherapy drugs, leading to fewer side effects. It’s…

Pharmacology

Rutgers To See If Targeted Chemotherapy Is Working

The study find that the Rutgers researchers have created a device that can determine whether targeted chemotherapy drugs are working on individual cancer patients. The portable device; which uses artificial intelligence and biosensors, is up to 95.9 percent accurate in counting live cancer cells when they pass through electrodes, according to a study in the journal Microsystems &…

pharmacology

Chemotherapy Safe, Effective For Certain Children

The researches find that the Children with hepatoblastoma resected at diagnosis demonstrated disease control with a minimal postoperative chemotherapy regimen, according to results from a phase 3 Children’s Oncology Group trial published in The Lancet Oncology. The regimen consisted of two cycles of cisplatin, fluorouracil and vincristine; instead of the usual four to six cycles, after…

Pharmacology

The Most Effective Chemotherapy Drugs: 5-Fluorouracil

The first scientist to have unlocked a long-standing mystery as to why some cancers do not respond to treatment with one of the most effective chemotherapy drugs: 5-Fluorouracil (5-FU). now working to develop a drug that will make 5-FU effective in cancers previously resistant to treatment,” Associate Professor Puthalakath said. The research also has potential…

Pharmacology

Advanced Cancer Are To Test a Therapy Aimed at Reducing Symptoms

The researches find that the Patients with advanced cancer are to test a therapy aimed at reducing their symptoms and improving quality of life. Therefore The treatment  called bermekimab could help with improving outcomes in cancer, including reducing symptoms such as weight loss and decreased mobility. Researchers have been award almost £1 million from the…

Pharmacology

Treatment Target For Rare Liver Cancer In Adolescents

The study find that the protein promotes a rare form of liver cancer in adolescents and young adults. The researchers also saw that a certain mix of drugs could target the fused protein and the enzymes that it recruits. Therefore In the lab, this drug combination slowed down the uncontrolled growth of cells carrying the…

Pharmacology

Therapeutics’ Neuromodulation System Treats Phantom-Limb Pain

The researches find that the Medical device company SPR Therapeutics makes a neuromodulation system in Minnesota that can treat pain in a person’s limbs even limbs that were amputated long ago. Treating phantom-limbpain is just one of the applications for the Sprint peripheral nerve stimulation (PNS) system; a medical device that has been shows to…

Pharmacology

Small Cell Cancers to Blood Cancers Lead to Better Treatments

The researches find that the scientists has find that small cell neuroendocrine cancers from a range of tissues have a common molecular signature and share drug sensitivities with blood cancers. Therefore The discoveries could improve the diagnoses of these aggressive cancers and lead to the development of new treatments that build upon the lessons learned…

Pharmacology

Lights Way for Chemo-Free Therapy in Colorectal Cancer

New results from the BEACON clinical trial offer hope for a chemotherapy-free treatment option for certain patients with colorectal cancer (CRC). Combinations of targeted therapies yielded significantly improved response rates and overall survival rates compared with traditional; chemotherapy regimens among patients with previously treated BRAF V600E–mutated metastatic CRC. This BRAF V600E mutation is found in 10% to 15%…

Pharmacology

New Drug Combinations and Dosing Improve Colon Cancer

The researches find that the a new drug for colon cancer often spreads widely and may not respond to standard chemotherapy. In such a case; a novel combination of drugs and flexible dosing may help achieve a better outlook; as demonstrated by several new studies. In one study, investigators explored the use of paclitaxel in…

Pharmacology

To Improve Identification and Treatment of Sepsis

Today the UK Sepsis Trust (UKST) announces findings from an APPG report on sepsis, revealing that the overwhelming majority of Trusts and hospitals use clinical tools developed by the UK Sepsis Trust. The report found that 80% of Trusts surveyed are using UKST’s recognition pathway; Red Flag Sepsis and that nearly 100% of Trusts are…