Chemicals produced by vegetables such as kale, cabbage, and broccoli could help to maintain a healthy gut and prevent colon cancer, a new study from the Francis Crick Institute shows
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To encourage innovation in healthcare, governments need to move away from current siloed funding to funding that encourages collaboration among providers in managing patients who need care in a variety of settings, argue the authors of CMAJ (Canadian Medical Association Journal).
Investigators have discovered that arsenic in combination with an existing leukemia drug works together to target a master cancer regulator. The team, led by researchers at the Cancer Center at Beth Israel Deaconess Medical Center (BIDMC), is hopeful that the discovery could lead to new treatment strategies for diverse types of cancer. Their findings were published today online in Nature Communications
An Atlas-award winning study reported in the Journal of Ethnopharmacology has found that traditional uses of medicinal plants in the Peruvian rainforest are, to a large extent, backed up by science. Samples taken from plants identified by people from the Iquitos-Nauta road communities and studied in the lab have been found to contain extracts that are harmful to protozoan parasites responsible for malaria and other infectious conditions common in the tropics.
A cancer drug that boosts the immune system outperforms chemotherapy in fighting advanced lung cancer, a new trial shows. Keytruda (pembrolizumab) extended life four to eight months longer than chemotherapy in lung cancer patients whose immune systems had been duped by their cancer cells.
Understanding that not all bladder cancers are the same, researchers at the University of North Carolina Lineberger Comprehensive Cancer Center have created a tool that may help them to uncover why only a fraction of patients responds to new immune-based treatments.
Salbutamol, also known as albuterol, is a medication that opens up constricted medium and large airways in the lungs and is often used to treat asthma. Because high doses are suspected by some to also have an anabolic effect, its daily dosage is restricted by the World Anti-Doping Agency, which uses urine tests to determine violations. A new British Journal of Clinical Pharmacology study shows that large variability in urine concentrations, however, lead to infeasibility of determining an administered dose from a single untimed urine sample.
According to a new study, the mineralocorticoid-receptor blocker eplerenone improves some metabolic and inflammatory indices in patients infected with HIV.
The study describes an approach to modeling the characteristics of early human cardiac organogenesis , which creates the necessary geometric confinement to drive the spatial organization of human induced pluripotent stem cells (hiPSCs).
Vascular endothelial growth factor-C, a lymphangiogenic growth factor results in cell proliferation and survival. The interruption of VEGF-C signaling might be a potential therapeutic target for antileukemic treatment in AML patients.
The researchers found that Splenda (an artificial sweetener) ingestion resulted in increased myeloperoxidase activity in the intestines of the mice with the bowel disease, but not in the healthy mice.