All news from Pharmacology and Therapeutics

Study Finds New Mechanism for Regulating Sleep Using an Ingredient Commonly Found in Energy Drinks

Sleep is an essential behavioral state in animals ranging from invertebrates to humans. It is critical for immune function , stable metabolism, brain repair, learning, and memory. Over the course of a lifetime, more than 30 percent of people will experience a sleep disorder, which is associated with a number of diseases including Alzheimer's, type 2 diabetes, and cardiovascular disease

Will Tarloxotinib Finally Break the HER2 Barrier in Lung Cancer?

The HER2 gene is a well-known driver of breast cancer, where changes in this gene are found in about 1-in-5 cases of the disease. HER2 also contributes to about 3 percent of lung cancers, representing about 6,500 patients per year. But while drugs like trastuzumab and lapatinib have proven effective in silencing the action of HER2 in breast cancer, there are currently no approved HER2-targeted therapies for the treatment of lung cancer