All news from Pharmacology and Therapeutics

Dose of Medication

Artificial Intelligence To Adjust Chemotherapy Dosages

Finding the right dose of medication by trial and error can be a painful experience for patients who are already suffering because of their disease. Artificial intelligence can greatly accelerate this process thanks to a new algorithm created by Adrien Coulet; in collaboration with researchers from Stanford University. By analyzing patients’ digital data; this innovative…

Artemisinins

Finding New Anti-Malaria Drug Reported

Malaria is a mosquito-borne infectious disease affecting humans and other animals caused by single-celled microorganisms belonging to the Plasmodium group. Malaria causes symptoms that typically include fever, tiredness, vomiting, and headaches. In severe cases, it can cause yellow skin, seizures, coma, or death. Artemisinin is derived from the leaves and flowers of the annual mugwort (Artemisia annua) and been used in traditional Chinese medicine for centuries. Chinese researcher Tu Youyou recently tested its effectiveness;…

Drug

Drug Compounds In Treating Acute Myeloid Leukemia

Researchers have been struggling for years to find a treatment for patients who have a recurrence of acute myeloid leukemia (AML), an aggressive blood cancer that is one of the most lethal cancers. About 19,520 news cases are diagnosing a year, and about 10,670 people a year die from it, according to the American Cancer…

Fecal incontinence

Treatment Options For Fecal Incontinence

Fecal incontinence, or accidental stool leakage, affects some 8 to 10 % of the 325 million people in the United States. In up to half of patients, there is both fecal and urinary incontinence. “Not all patients with incontinence are the same. There are some with muscle injuries, some with nerve injuries, some with more…

Rural communities

Method For Estimating Rural Intravenous Drug Use

A study published today in the American Journal of Public Health estimates that 1,857 people injected drugs in the last six months in Cabell County; a rural county with a population of 94,958. This estimate is based on an innovative survey technique. Public health officials can now use in their own rural communities to address the…

Benzodiazepines

In Outpatient Increasing Benzodiazepine Use

Quantified patterns in outpatient benzodiazepine prescribing and compared them across specialties and indications using nationally representative. The yearly population-based sample of outpatient visits among adults; was analyzed and ranged from 20,884 visits in 2003 to 24,273 visits in 2015. Benzodiazepines Benzodiazepines (BZD, BDZ, BZs), sometimes called “benzos” are a class of psychoactive drugs whose core chemical structure is the fusion of a benzene ring…

Biological clock And This Drug May Keep It From Ticking

A new drug shows potential to halt cancer cells' growth by stunting the cells' biological clock. The findings from scientists at the USC Michelson Center for Convergent Bioscience and Nagoya University's Institute of Transformative BioMolecules (ITbM) advance a burgeoning area of research: turning the body's circadian rhythms against cancer.

Aspirin Lowers Stroke Risk In Women With History Of Preeclampsia

A new study suggests aspirin may lower stroke risk among middle-aged women with a history of preeclampsia. Middle-aged women with a history of preeclampsia have a greater risk of stroke, and aspirin may be able to reduce the risk, according to a new study led by researchers at Columbia University Vagelos College of Physicians & Surgeons. The study was published today in the journal Neurology, along with an accompanying editorial and podcast.

Drug For Treating Liver Parasites In Vivax Malaria

Vivax malaria is a serious illness with a high fever that, if untreated, can keep people bed-ridden for weeks or even months. But even after successful treatment, it's tricky: although the current, commonly-used drugs successfully treat the blood stage of vivax malaria, they are unable to prevent malaria parasites from invading the liver (liver stage) and causing the disease to recur repeatedly over many years. 

Pembrolizumab Survival In Patients With Squamous Cell Carcinoma

Squamous cell carcinoma is one of the most common cancers of the skin and mucosa. Treatment options for the advanced stage have been very limited for patients with tumors of the head and neck, i.e. in the mouth, the pharynx or the larynx: If recurrences or metastases occur during or after platinum-based chemotherapy, the disease is generally considered incurable. The goal is then to prolong the remaining lifetime while maintaining the best possible quality of life.