All news from Pathology & Microbiology

Pathological Description Of Parkinson's Disease

Pathological Description Of Parkinson’s Disease

The study demonstrating that a gut infection can lead to a pathology; resembling Parkinson’s disease (PD) in a mouse model lacking a gene linking to the human disease. The study suggesting that Parkinson’s disease has a major immune component; providing new avenues for therapeutic strategies. As Parkinson’s disease is causing by the progressive death of…

Mechanism Behind Development Of Viral Infections

Mechanism Behind Development Of Viral Infections

Flaviviral infections, a family of viral infections transmitted by mosquitoes and ticks; are major health concerns as they spread rapidly and lack licensing treatments. Implications for the prevention and treatment of infectious diseases causing by flaviviral infections such as dengue fever; congenital Zika syndrome and yellow fever. Flaviviral infections result in a wide spectrum of clinical…

Coccidioidomycosis Life Threatening Form

Coccidioidomycosis Life Threatening Form

Coccidioidomycosis commonly knowing as Valley Fever; which will recover without treatment and those with more serious cases will require an antifungal medication that clears the infection. But a few will experience a life threatening form of the disease that ravages the body for reasons unknown. Coccidioides, the fungus commonly finding in soil that causing Valley…

Conformational Changes Plague Pathogens Yersinia

Conformational Changes Plague Pathogens Yersinia

The spread fear and terror, especially in the past; but today the plague pathogens have still not been completely eradicating. The bacteria inject various enzymes, including the enzyme YopO, into the macrophages of the immune system. There it is activating and prevents the defense cells from enclosing and digesting the plague bacteria. Yersinia also includes…

The Mechanism Of Replication Prions In Mad Cow Disease

The Mechanism Of Replication Prions In Mad Cow Disease

Prions are unusual infectious agents made by aberrantly folded forms of a physiological protein called the cellular prion protein, or PrPC. These pathogens are knowing to replicate in absence of genetic material by recruiting normal PrPC molecules at the surface of cells and forcing them to change conformation and becoming infectious themselves. The study reporting a…

Drug Provides For Duchenne Muscular Dystrophy Patients

Drug Provides For Duchenne Muscular Dystrophy Patients

Duchenne muscular dystrophy (DMD) is a genetic, neuromuscular disease in which a patient lacks dystrophin, a structural protein present within muscle cells. The researchers explaining that respiratory function can be measuring in several ways; one of which is the forced vital capacity (FVC); which is the total amount of air that can be exhaling by…

Mediated Cytokines Activation Of Human Natural Killer Cells

Mediated Cytokines Activation Of Human Natural Killer Cells

Cells mediate innate immunity through direct cell lysis by intracytoplasmic azurophilic granules; and modulation of other immune cells by release of proinflammatory cytokines; such as interferon (IFN)-ɣ and tumor necrosis factor (TNF). The effector function of NK cells is regulatingf by the balance; between activating and inhibitory receptor signals. In contrast, NK cell inhibition is…

Raw Meat Can Act As Reservoir For Bacteria

Raw Meat Can Act As Reservoir For Bacteria

The species like Acinetobacter calcoaceticus-Acinetobacter baumannii (ACB) complex are of particular clinical relevance, but often associating with nosocomial infections.  Although the isolates were susceptible to most antibiotics; these results suggesting that raw meat can act as a reservoir for these pathogenic bacteria. Bacteria of the Acinetobacter ACB complex; which are frequently acquiring in hospital settings, can…

Thrombus Producing Initial Hypoxic Damage

Thrombus Producing Initial Hypoxic Damage

The majority of strokes (87%) are ischemic and result from a thrombus obstructing a major artery in the brain; the blockage causing by the thrombus producing initial hypoxic damage that is following by ischemia and infammation. The analysis of blood samples from the injury site; allowing for a systematic understanding of ischemic stroke neuropathology at…

Chlamydia Trachomatis Serology In Conservative Management

Chlamydia Trachomatis Serology In Conservative Management

Chlamydia trachomatis (chlamydia) is the most prevalent bacterial sexually transmitted infection (STI); particularly among young sexually active women; the WHO estimating that the prevalence of chlamydia infection had increasing progressively over the past decade with 131 million new cases diagnosing annually worldwide. The most frequent clinical appearance of chlamydia infection is cervicitis among women and…

Low FODMAP Diet Showing Effect On Micronutrients Intake

Low FODMAP Diet Showing Effect On Micronutrients Intake

The FODMAPs are the fermentable oligosaccharides; Disaccharides, monosaccharides and polyols; which is triggering symptoms in IBS patients; Several studies have showing that a diet low in FODMAPs can improve IBS symptoms; and as a consequence low-FODMAP diet eating [micronutrients intaking] are now commonly using to manage the condition. But atients typically first restrict high-FODMAP foods…

Chan-Zuckerberg Initiative for Human Cell Atlas project

Chan-Zuckerberg Initiative for Human Cell Atlas project

Human Cell Atlas; Researchers from Joslin Diabetes Center have been selected by the Chan-Zuckerberg Initiative (CZI); but one of 38 collaborative science teams that will launch CZI’s Seed Networks for a Human Cell Atlas projects. These collaborative groups will bring together scientists, computational biologists; software engineers, and physicians to support the continued development of the…