Aging vessels connecting the brain and the immune system play critical roles in both Alzheimer's disease and the decline in cognitive ability that comes with time, new research reveals. By improving the function of the lymphatic vessels, scientists have dramatically enhanced aged mice's ability to learn and improved their memories. The work may provide doctors an entirely new path to treat or prevent Alzheimer's disease, age-related memory loss and other diseases.
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Researchers at the Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC) have provided valuable information about the defense mechanisms of the immune system during the early stages of the response to pathogens such as viruses and bacteria.
The research findings, published in Nature Communications, contribute to the understanding of the cellular processes initiated at early stages and explain how the distinct cell populations of the immune system communicate to mount an effective response against pathogens.
A team of researchers from the University of Wisconsin, the University of Iowa and the Norwegian Institute of Public Health has carried out genetic studies of tuberculosis to learn more about its lineage and to compare it with transmission pathways through early human migration.
They have outlined their study and results in a paper available on the bioRxiv preprint server. Team lead Caitlin Pepperell also presented the group's findings at this year's ASM Microbe 2018 meeting.
Infection with cytomegalovirus triggers long-lasting eye inflammation and establishes a dormant pool of the virus in the eyes of mice with healthy immune systems, according to new research presented in PLOS Pathogens by Valentina Voigt of the Lions Eye Institute in Western Australia and colleagues.
A new study shows that a kind of E. coli most associated with "travelers' diarrhea" and children in underdeveloped areas of the world causes more severe disease in people with blood type A. The study is published in The Journal of Clinical Investigation
A stem cell is one with infinite possibilities. So, for decades, scientists have puzzled over how the cell chooses to keep being a stem cell and continue dividing, or specialize into a specific cell type, like a heart or brain cell.
Biologists have discovered evidence for a new path of evolution and with it a deeper understanding of how quickly organisms such as viruses can adapt to their environment.
The researchers say their findings, which address longstanding mysteries of how genes acquire new functions and how mutations arise to ease transmission from one host to another, could be applied to investigations of viral diseases such as Zika, Ebola and bird flu.
Researchers have discovered a way the gonorrhea bacteria cleverly evade the immune system — opening up the way for therapies that prevent this process, allowing the body's natural defenses to kill the bug.
A new research showed that new tactic could help physicians decide whether or not to refer patients with prostate-specific antigen (PSA) levels high enough to suggest clinically significant prostate cancer.
New Artificial Intelligence (AI) software performed better than pathologists when it came to predicting overall survival in patients diagnosed with glioma, concludes a study published in the Proceedings of the National Academy of Sciences of the USA.
Fecal profiling of volatile organic compounds (VOCs) might provide a low-cost tool to predict the responses of irritable bowel syndrome (IBS) patients to diet low in fermentable oligosaccharides, disaccharides, monosaccharides, and polyols (FODMAPs).
Omega-3 Index was measured in 2500 participants in the Offspring cohort of the Framingham Heart Study. To assess individual's risk of developing certain diseases. A higher Omega-3 Index has been associated with a lower risk for total CVD events.