All news from Pathology & Microbiology

New Insights on Brain discovery, Aging's Terrible Toll on the Mind Blocked

Aging vessels connecting the brain and the immune system play critical roles in both Alzheimer's disease and the decline in cognitive ability that comes with time, new research reveals. By improving the function of the lymphatic vessels, scientists have dramatically enhanced aged mice's ability to learn and improved their memories. The work may provide doctors an entirely new path to treat or prevent Alzheimer's disease, age-related memory loss and other diseases.

Antiviral Reponsese Initiated with Mitochondrial DNA in Exosomes

Researchers at the Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC) have provided valuable information about the defense mechanisms of the immune system during the early stages of the response to pathogens such as viruses and bacteria.

The research findings, published in Nature Communications, contribute to the understanding of the cellular processes initiated at early stages and explain how the distinct cell populations of the immune system communicate to mount an effective response against pathogens.

Tuberculosis: Lineage Traced And Compared to Early Human Migration

A team of researchers from the University of Wisconsin, the University of Iowa and the Norwegian Institute of Public Health has carried out genetic studies of tuberculosis to learn more about its lineage and to compare it with transmission pathways through early human migration.

They have outlined their study and results in a paper available on the bioRxiv preprint server. Team lead Caitlin Pepperell also presented the group's findings at this year's ASM Microbe 2018 meeting.

Virus Adapts Newly Discovered Path of Evolution

Biologists have discovered evidence for a new path of evolution and with it a deeper understanding of how quickly organisms such as viruses can adapt to their environment.

The researchers say their findings, which address longstanding mysteries of how genes acquire new functions and how mutations arise to ease transmission from one host to another, could be applied to investigations of viral diseases such as Zika, Ebola and bird flu.

Fecal Profiling: Tool To Predict Responses Of IBS

Fecal profiling of volatile organic compounds (VOCs) might provide a low-cost tool to predict the responses of irritable bowel syndrome (IBS) patients to diet low in fermentable oligosaccharides, disaccharides, monosaccharides, and polyols (FODMAPs).