An infant born with a relatively simple heart defect is far more likely to develop heart problems as an adult; researchers at the Stanford University School of Medicine have discovered. The risk is so great that someone born with a heart defect who has a heart-healthy lifestyle is twice as likely to develop heart problems as someone born without a defect who has a heart-averse lifestyle.
“All of us in cardiology recognize that people with the complex disease need follow-up care throughout their lives;” said James Priest, MD, assistant professor of pediatric cardiology. “But for the simple problems; they have thinking that once you close the hole or fix the valve; these patients are good to go.” The research findings suggest that the medical community should watch adults who were born with heart defects even minor ones more carefully.
Common congenital condition
About 1 % of infants are born with heart defects, the most common congenital condition. Those with less-complex defects, such as a hole in the heart or a faulty valve, nearly always survive into adulthood; sometimes unaware of the defect until later in life. To conduct their research, Priest, Saha and their colleagues mined data from the U.K. Biobank; which includes health data on 500,000 British residents aged 37 to 73 during the biobank’s recruitment period from 2006 to 2010.
They found 2,006 people who had mild congenital heart defects. For reasons the researchers don’t understand, the members of this group slightly more likely to obese, to smoke; to have high blood pressure and to have diabetes all factors that increase the risk for cardiovascular problems. However, even after adjusting for those risk factors; they found that those born with mild heart defects were 13 times as likely to develop heart failure or atrial fibrillation; five times as likely to have a stroke, and twice as likely to suffer a heart attack than those born without heart defects.
Congenital heart defects
Adult survivors of congenital heart defects with fewer risk factors for heart disease such as smoking, having high blood pressure and being obese fared better than those who had more risk factors. Those with a heart-healthy lifestyle were about a third less likely to develop heart conditions than those with five or more heart disease risk factors. It is unclear why adults who were born with heart defects suffer more heart disease, the study said.
Saha said further research into why congenital heart disease leads to adult heart problems could help shape follow-up care. But physicians can begin helping these patients right away by providing more surveillance. “That’s something that can change right now,” she said. “We can start connecting them with cardiology specialists.”