All news from Ophthalmology

Thyroid Eye Disease

Teprotumumab Benefit In Thyroid Eye Disease

In a special hour-long late-breaker presentation; Douglas compared the new data with those from a phase 2 trial that also showed a significant reduction in proptosis (eye bulging); with teprotumumab. Improvements in proptosis response (reduction of ≥ 2 mm); clinical activity scores (CAS) similar in both studies, he said. In the United States, about 15,000…

Ultraviolet radiation

Ultraviolet Radiation Exposure Dose And Cataract In China

Many studies have reported ultraviolet (UV) radiation to be a risk factor for cataract. Although the onset of anterior cortical cataract has reported caused by UVB exposure through some animal experiments; most reports have assessed the application of much stronger UVB exposure than the normal daily exposure dose. To the best of our knowledge; no…

Eye disease

Discover Link Between Vascular Biology And Eye Disease

In a series of studies that volleyed between large databases and research in zebrafish; Vanderbilt investigators have discovered a link between vascular biology and eye disease. But the researchers uncovered an unexpected role for the gene GRIK5, and it showcases a new paradigm for using biobanks; electronic health records, and zebrafish to discover the genetic…

Fireworks Injuries

Ocular Fireworks Injuries In Eastern Nigeria

Fireworks commonly as “bangers” or “knockouts” are widely used in Nigeria during festivities such as Christmas; New Year, Eid-Maulud, Independence Day, and sporting activities. Fireworks are used in different parts of the world to commemorate national and religious events. The use of fireworks for purposes of celebration is with fireworks casualties. Eye injuries from fireworks…

Visually Impaired Children

Using Braille Text In A Group Of Visually Impaired Children

Oral health is a vital component of overall health; which contributes to each individual’s well-being and quality of life by positively affecting physical, social and mental health, appearance, and interpersonal relations. Special and medically compromised patients present unique challenges to the dentist’s skills and knowledge. It has observed with adequate training and understanding of the…

Eye

Microglia Play Vital Role In Regulating Neuroinflammation

A research team at Massachusetts Eye and Ear have shown that microglia; the primary immune cells of the central nervous system including the retina of the eye serve as “gatekeepers,” or biosensors and facilitators; of neuroinflammation in a preclinical model of autoimmune uveitis. Uveitis is one of the leading causes of blindness; accounting for approximately…

Optic neuropathies

Plasma Levels Of Drebrin In Glaucoma Patients With Neurodegeneration

Glaucoma comprises a group of optic neuropathies by progressive degeneration of RGCs; resulting in characteristic changes in the ONH and RNFL, and VF defects. The biological basis of glaucoma is poorly understood, and the factors contributing to its progression have not been fully characterized. Diagnosis of glaucoma is by a combination of identifying characteristic changes…

Macular hole

Closure Of Idiopathic Full-Thickness Macular Hole

Idiopathic macular hole (IMH) is a kind of disease that seriously affects the visual quality of patients, showing obvious central visual loss and visual deformation. The AAO guidelines suggest that stage 2–4 IMHs have a good prognosis after vitrectomy surgery, which can effectively improve the central visual acuity and reduce metamorphopsia. The closure rate after…

Macula

Drugs That Have Potential To Treat AMD

Macular degeneration is an eye disorder by a number of conditions negatively affecting the macula. The macula is also as the ‘yellow spot’ a miniscule; specialized region of the retina containing photoreceptor cells (cone cells); responsible for central sight in conditions of bright lighting in order to distinguish fine detail and color. Flanking the central…

Vision loss

Drug Delivers One-Two Punch To Vision Loss

In studies with lab-grown human cells, Johns Hopkins Medicine researchers have found that an experimental drug; may twice as good at fighting vision loss as previously thought. The new research shows that the compound, named AXT107; stops abnormal blood vessels in the eye from leaking vision-blocking fluids. These results build on previous research that showed…

Babies Avoid Vision Problems

Light Therapy: Premature Babies Avoid Vision Problems

Scientists discovered a light-dependent molecular pathway that regulates how blood vessels develop in the eye. The findings in Nature Cell Biology suggest it may possible to use light therapy to help premature infants whose eyes are still developing avoid vision problems. Called the opsin 5-dopamine pathway; the novel molecular process helps ensure blood-vessel development in the…

Superposition eyes

Superimposition Of Eye: Analysis From Large Public Health

Superposition eyes produce real, erect images on a retina separated from the optical elements by a clear zone. In refracting superposition eyes, the optical elements may lens cylinders or corneal lens/lens cylinder combinations. These act as inverting telescopes. Resolution can as good as in an apposition eye with similar-sized facets; the sensitivity is usually much…