All news from Obstetrics & Gynaecology

Embryo

Single-Cell Sequencing To Get Better Look At Human Embryo Implantation

A team of researchers affiliated with multiple institutions in China has used single-cell sequencing; to learn more about the human embryo during implantation in the uterus. In their paper published in the journal Nature; the group describes sequencing thousands of human embryo cells from before, during and after implantation, and what they learned from it.…

Sleep Disturbances

Risk Of Sleep Disturbances In Menopausal Women

Women with diabetes undergoing the menopause transition are at greater risk for sleep disturbances, according to new findings. Hormone changes have known to alter insulin sensitivity and glucose metabolism, as well as interfere with women’s sleep patterns. But little is known about the association between diabetes and sleep disturbances during the menopause transition until now.…

Suicidal thoughts

Hormone Levels Can Control The Suicidal Thoughts In Women

University of Illinois at Chicago researchers are trying to help women; who have a history of suicidal thoughts by looking at how the hormones estrogen and progesterone; which fluctuate during the menstrual cycle, can affect their mood. Researchers recently obtained a $3.1 million grant from the National Institute of Mental Health; to further study how…

Link Between Elevated Hormone Levels In Womb And Autism

Link Between Elevated Hormone Levels In Womb And Autism

A small new study has once again found a link between elevated hormone levels in the womb and the likelihood of developing autism. But this time, instead of major androgens such as testosterone, researchers are pointing the finger at estrogen. Currently, prenatal hormones such as androgens and estrogens are thought to influence the development of a…

Endometriosis

Endometriosis Linked To Adverse Pregnancy Outcomes

Endometriosis associated with increased risk for specific adverse pregnancy outcomes; including spontaneous abortion, ectopic pregnancy, and preeclampsia, according to results of a study published today in Obstetrics and Gynecology. But endometriosis is often associated with pelvic pain and infertility; but more than 80% of affected women do become pregnant. Leslie V. Farland, ScD, from the…

Ovarian Cancer

Researcher Identify Protein Governing Platinum Resistant Ovarian Cancer

Up to 80% of patients with ovarian cancer develop platinum resistance over time to platinum-based chemotherapy. Increased HIF1α level is an important mechanism governing platinum resistance in platinum-resistant ovarian cancer (PROC). However, the mechanism regulating HIF1α stability in PROC remains largely unknown. Here, they elucidate the mechanism of HIF1α stability regulation in PROC; and explore…

Vaginal microbiome

Cervicovaginal Microbiome Can Elicit Resistance To chlamydia

Vaginal microbiome is believed to protect women against Chlamydia trachomatis; the etiological agent of the most prevalent sexually transmitted infections (STIs) in developed countries. New research by the University of Maryland School of Medicine (UMSOM) shows how the microbiome can either protect or make a woman more susceptible to these serious infections. The research is…

Ovarian Cancer

Advanced Ovarian Cancer Drug Gets Initial ‘No’ For NHS In England

A targeted drug with potential to slow the progress of ovarian cancer has rejected for use on the NHS in England. In making its provisional decision on rucaparib (Rubraca); the National Institute of Health and Care Excellence (NICE) cited a lack of evidence over the treatment’s impact on survival. “NICE felt there was not enough…

Ovarian Cancer

Managing Ovarian Cancer Risk In Women With BRCA1/2 Genetic Variants

BRCA1 and BRCA2 genetic variants are a clinically important risk factor for the development of ovarian and breast cancer; and women who carry these variants have a lifetime risk of ovarian cancer of 39%-44% and 11%-17%, respectively. “Given the substantial lifetime risk and high mortality of ovarian cancer in women with BRCA1/2 variants, risk reduction…

Reproductive Coercion

Nearly 1 In 8 Teens Experience Reproductive Coercion, Reports Say

Female adolescents are experiencing relationship abuse at alarming rates; according to a new Michigan State University study that specifically researched reproductive coercion a form of abuse in which a woman is pressured to become pregnant against her wishes. Heather McCauley, assistant professor in the School of Social Work; and co-researchers found nearly one in eight…

Menopause

Doctors Say That Menopause Might Be Delayed

A fertility expert, who pioneered In Vitro Fertilization (IVF), may have found a breakthrough medical treatment ideal for women up to 40 years old, who wants to give birth even after they have reached the age of menopause. Thousands of women will benefit from a breakthrough medical procedure that can delay menopause for as long…

Endometrial diseases

Endometrial Diseases Can Be Imitated In A Lab Dish

Endometrial diseases represent a major gynaecological burden. Biomedical researchers at KU Leuven have found a new way to study endometrial diseases such as endometriosis and cancer. They were able to grow three-dimensional cell structures from diseased tissue of patients. The biobank can be used to unravel the disorders and test drugs. Diseases of the endometrium…