Whether baseline metabolic tumor volume (TMTV) and total lesion glycolysis (TLG) measured by FDG-PET/CT affected prognosis of patients with lymphoma was controversial. We searched PubMed, EMBASE and Cochrane to identify studies assessing the effect of baseline TMTV and TLG on the survival of lymphoma patients. Pooled hazard ratios (HR) for overall survival (OS) and progression-free survival (PFS) were calculated, along with 95% confidence intervals (CI).
All news from Nuclear Medicine
In this work we present a methodology able to use harmonized PET/CT imaging in dose painting by number (DPBN) approach by means of a robust and accurate treatment planning system. Image processing and treatment planning were performed by using a Matlab-based platform, called CARMEN, in which a full Monte Carlo simulation is included.
As part of the EXPLORER total-body positron emission tomography (PET) project, we have designed and built a high-resolution, high-sensitivity PET/CT scanner which is expected to have excellent performance for companion animal whole body and human brain imaging. The PET component has a ring diameter of 52 cm and an axial field of view of 48.3 cm.
This study aimed to assess the therapeutic impact and diagnostic accuracy of 18F-DOPA PET/CT in patients with glioblastoma or brain metastases. Gliomas and metastases are the most common malignant brain tumors. Brain metastases arise in 10–40% of systemic cancers with non-small cell lung cancer being the primary tumor in about half of the patients
Using a common type of brain scan, researchers programmed a machine-learning algorithm to diagnose early-stage Alzheimer's disease about six years before a clinical diagnosis is made potentially giving doctors a chance to intervene with treatment.
Cardiac PET / MRI acquisition presents novel clinical applications thanks to the combination of viability and metabolic imaging (PET) and functional and structural imaging (MRI). However, the resolution of PET, as well as cardiac and respiratory motion in non-gated cardiac imaging acquisition protocols, leads to a reduction in image quality and severe quantitative bias. Respiratory or cardiac motion is usually treated with gated reconstruction which results in higher noise.
To evaluate the feasibility of ultrasound (US) computed tomography (CT) or magnetic resonance imaging (MRI) fusion imaging (FI) for localization and assessment of kidney lesions.
Radiotherapy for the treatment of left-sided breast cancer increases the long term risk of cardiovascular disease. The purpose of this study was to non-invasively image the progression of radiation-induced cardiac inflammation in a large animal model using a hybrid positron emission tomography and magnetic resonance imaging system.
A new radioactive tracer molecule that binds to the Alzheimer's protein tau has been developed that may help in diagnosis and monitoring of the disease, as well as in the development of new drugs for the condition.
To determine the predictive and diagnostic value of 68Ga-HBEDD PSMA-11 PET/CT (PSMA) for surgical response in males with prostate cancer prior to radical prostatectomy.
Because of the low incidence of primary central nervous system lymphoma (PCNSL) in non-HIV individuals and because of the lack of specific clinical manifestations and auxiliary examinations, the disease is easily missed or misdiagnosed.
Despite a high distribution rate of stable iodine after the 2011 Fukushima nuclear accident in Japan, only 63.5% of parents reported having taken the tablets, with many citing safety concerns in questionnaires, according to findings published in The Journal of Clinical Endocrinology & Metabolism.