Since its introduction, positron emission tomography (PET) fused with computed tomography (CT) (PET/CT) has gained a crucial role in the everyday clinical practice of medical imaging, particularly in oncology for both solid tumors and lymphomas. 18F-fluorodeoxyglucose (18F-FDG) has long been the radiopharmaceutical of choice for the PET/CT evaluation of oncology patients. Evaluation of Intracranial Lesions…
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To construct a tumor voxel Dose Response Matrix (DRM) and Dose Prescription Function (DPF) for adaptive Dose Painting by Number (DPbN) based on treatment feedback of FDG-PET/CT imaging. The uniform prescription dose, which has been safely used in clinics, has significant limitations to destroy local resistant niches in tumors that cause radiotherapy failures. Hence the…
COPD is a complex and heterogeneous condition in which neutrophils play a central role. Studying neutrophil accumulation across all lung compartments is challenging due to a lack of direct ‘whole lung’ assessment techniques. The aim of this study was to validate a new non-invasive method for measuring whole lung neutrophil accumulation in patients with stable…
According to the current guidelines, arterial hyperenhancement for diagnosis of hepatocellular carcinoma (HCC) is determined using the arterial phase only. We investigated the optimal definition of arterial hyperenhancement in patients with HCC using computed tomography (CT) and magnetic resonance imaging (MRI).
High-field micro-magnetic resonance imaging (MRI) scanning may provide additional information for quantitative analysis of graft bone healing processes, thus serving as a promising supplementary method in graft and bone healing evaluation following anterior cruciate ligament reconstruction (ACLR) surgery during preclinical studies.
The aim of the present study was to evaluate the curative effect of fludeoxyglucose-positron emission tomography/computed tomography (18F-FDG-PET/CT) guided intensity-modulated radiotherapy (IMRT) for 42 patients with International Federation of Gynecology and Obstetrics (FIGO) stage III/IV ovarian cancer.
The most frequently used methods of assessing Graves’ orbitopathy (GO) include Clinical Activity Score (CAS), ultrasonography (USG), computed tomography (CT), and magnetic resonance imaging (MRI). There exists another, slightly forgotten, imaging method: single-photon emission computed tomography (SPECT) with the use of diethylenetriaminepentaacetic acid tagged with 99mTc (99mTc-DTPA).
Many medical imaging techniques use fitting approaches for quantitative parameter estimation and analysis. Common examples are pharmacokinetic modeling in dynamic contrast-enhanced (DCE) magnetic resonance imaging (MRI) / computed tomography (CT), apparent diffusion coefficient calculations and intravoxel incoherent motion modeling in diffusion-weighted MRI and Z-spectra analysis in chemical exchange saturation transfer MRI.
In PIK3CA mutant breast cancer, downstream hyperactivation of the PI3K/AKT/mTOR pathway may be associated with increased glycolysis of cancer cells. The purpose of this study was to investigate the functional association of PIK3CA mutational status and tumor glycolysis in invasive ER+/HER2- early breast cancer.
The objective of our study was to identify the clinical features and imaging findings of the abdominal compartment syndrome (ACS) in children. During the study, ACS was diagnosed in 50 children, 14 of whom underwent CT or MRI. We reviewed the medical records of the 50 children to obtain clinical information, such as underlying risk factors, therapeutic approach, and clinical outcome, and we evaluated the CT and MRI examinations of the 14 children.
The aims of the study were: 1- critical assess the utility of L-3,4-dihydroxy-6-18Fluoro-phenyl-alanine (18F-DOPA) and O- (2-18F-fluoroethyl) -L-tyrosine (18F-FET) positron emission tomography (PET) / computed tomography (CT) in patients with high grade glioma (HGG) and 2- describes the results of 18F-DOPA and 18F-FET PET / CT in a case series of patients with recurrent HGG.
Developed over decades, pulmonary oscillometry has re-emerged as a noninvasive and effort-independent method for evaluating respiratory-system impedance in patients with obstructive lung disease.