About 3.4 million Americans, or 1.2 percent of the population, have active epilepsy. Although the majority respond to medication, between 20 and 40 percent of patients with epilepsy continue to have seizures even after trying multiple anti-seizure drugs. Even when the drugs do work, people may develop cognitive and memory problems and depression, likely from the combination of the underlying seizure disorder and the drugs to treat it. The study is published in the journal Proceedings of the National Academy of Sciences
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Researchers at the University of Eastern Finland have discovered new changes occurring in the human brain in the early stages of Alzheimer's disease. The researchers used a multiomic approach to determine RNA, protein, and phosphorylation levels and carried out further neurobioinformatic analyzes on them. The findings, drawing on data from a Finnish biobank of brain tissue samples, were published in Neurobiology of Disease.
Dementia is common to a variety of neurodegenerative diseases such as Alzheimer's disease (AD), Parkinson's disease (PD) and Down syndrome (DS). This characteristic symptom is one of the significant causes of disability and dependency among older people. Worldwide, around 50 million people have dementia, and there are nearly 10 million new cases every year.
In Florida, there are more than 540,000 people living with Alzheimer's disease (AD), the most recognized form of dementia. The number of people in Florida who are age 65 and older with AD is expected to increase by 41.2% by 2025 to a projected 720,000, highlighting the urgency of finding medical and treatment breakthroughs.
Some neurons in the brain protect themselves from Alzheimer's with a cellular cleaning system that sweeps away toxic proteins associated with the disease, according to a new study from Columbia University and the University of Cambridge.
Pain is a negative feeling that we want to get rid of as soon as possible. In order to protect our bodies, we react for example by withdrawing the hand. This action is usually understood as a consequence of the perception of pain.
A team from the Technical University of Munich (TUM) has now shown that perception, the impulse to act and provision of energy to take the place in the brain simultaneously and not, as was expected, one after the other.
Caffeine plus another compound in coffee beans' waxy coating may protect against brain degeneration, Rutgers study finds. Rutgers scientists have found a compound in coffee that may team up with caffeine to fight Parkinson's disease and Lewy body dementia – two progressive and currently incurable diseases associated with brain degeneration.
Stroke is a leading cause of death and chronic disability in adults, causing a heavy social and economic burden worldwide. However, no treatments exist to restore neuronal circuitry after a stroke.
Two types of cells are active in the brain: nerve cells and glial cells. Glial cells have long been regarded primarily as supportive cells, but researchers increasingly recognize that they play an active role in the communication between neurons in the brain. Additionally, according to current research, glial cells are also involved in the development of neurodegenerative diseases.
Disorders of sleep are some of the most common problems experienced by patients after traumatic brain injury (TBI). It is important to recognize and treat these problems early to allow for optimal cognitive recovery, but because they are so common, the importance of treating them is often underestimated.
The kicks a mother feels from her unborn child may allow the baby to 'map' their own body and enable them to eventually explore their surroundings, suggests new research led by UCL in collaboration with UCLH.
Now one of the pioneers of 'optogenetics' and colleagues have created two new tools—protein pores which when illuminated allow Ca2+ into cells or K+ out—for switching neurons on or off using light. Published in Frontiers in Neuroscience, their study shows that these synthetic 'ion channels' can be used to control specific neurons, even in live animals