All news from Neurology

Neurons Interact

Understanding Of The Mechanisms Behind Neuropathic Pain

In the models of a totally crushed peripheral nerve, the damage axons are broken; allowing healthy ones to regrow. But humans rarely suffer complete axonal damage. Instead, axons tend to be partially damaged, causing neuropathic pain a difficult-to-treat; chronic pain associated with nerve trauma, chemotherapy, and diabetes. Explore the role of immune cells in breaking…

Brain

When It Comes To Brain Connectivity Cell Location Matters

A University of California, Irvine-led study reveals that connectivity within the brain. It appears to largely dictate by spatial architecture rather than cell type-specific cues. To understand how the brain works; current neuroscience research has focused on mapping the connect to determine how the brain is built and how it is wired. Much research has done…

Nervous system

Serotonin: Execute Instantaneous Behaviors

Known for its role in relieving depression, the neurochemical serotonin may also help the brain execute instantaneous; appropriate behaviors in emergency situations, according to a new Cornell study published in Science. Serotonin or 5-hydroxytryptamine (5-HT) is a monoamine neurotransmitter. It has a popular image as a contributor to feelings of well-being and happiness, though its actual biological function is complex and…

Myasthenia Gravis

Myasthenia Gravis Surgery To Remove Thymus Gland

Surgery to remove the thymus gland in patients with myasthenia gravis (MG); a rare autoimmune disease affecting neuromuscular function, provides significant clinical benefits for as long as five years after the procedure. The study followed 68 patients for up to five years after undergoing thymectomy, the surgical removal of the thymus gland. The benefits they exhibited…

The Physical Activity May Preserve Memory In Seniors

Adding to the growing body of evidence that physical activity has a positive impact on cognition, new research shows that these benefits may even extend to older adults with blood and brain biomarkers of Alzheimer's disease (AD) and other common age-related brain pathologies. More total daily activity and better motor abilities were each associated with a boost in cognitive reserve, investigators report.

Developing New Gene Therapy To Prevents Axon Destruction

Nerve axons serve as the wiring of the nervous system, sending electrical signals that control movement and sense of touch. When axons are damaged, whether by injury or as a side effect of certain drugs, a program is triggered that leads axons to self-destruct. This destruction likely plays an important role in multiple neurodegenerative conditions, including peripheral neuropathy, Parkinson's disease and amyotrophic lateral sclerosis (ALS).

Glial Cells Can Push Neurons Toward Parkinson's Disease

Researchers from the University of Barcelona have shown that defective versions of human brain cells called astrocytes are linked to the buildup of a toxic protein that is the hallmark of Parkinson's disease. The studied astrocytes, derived from Parkinson's disease patients with a genetic mutation that affects cell clean-up functions, caused more accumulation of the toxin, alpha-synuclein, than those derived from healthy individuals.