All news from Nephrology

Membranous Nephropathy

Rituximab Noninferior To Cyclosporine In Membranous Nephropathy

B-cell anomalies play a role in the pathogenesis of membranous nephropathy. B-cell depletion with rituximab may therefore be noninferior to treatment with cyclosporine; for inducing and maintaining a complete or partial remission of proteinuria in patients with this condition. Membranous Nephropathy (MN) is a kidney disease that affects the filters (glomeruli) of the kidney; and…

Oral Anticoagulants

Non-Vitamin K Oral Anticoagulants May Be Best For Early-Stage CKD

Effects of oral anticoagulation in chronic kidney disease (CKD) are uncertain. Non-vitamin K oral anticoagulants; (NOACs) have a superior benefit-risk profile to that of vitamin K antagonists (VKAs) for patients with early-stage chronic kidney disease (CKD); according to a review published in the Annals of Internal Medicine. However, patients who have advanced CKD or end-stage…

Kidney tumor

3D Printing To Improve Kidney Tumor Surgery

The surgical team at the CHU’sDepartment of Urology and Kidney Transplantationis 3D printing life-like transparent; and color models of the patient’s anatomy to help perform precise and successful kidney tumor surgery; and improve patient outcomes. Bordeaux University Hospital (CHU) in France is leading the charge to improve success rates; of complex kidney tumor removal surgery;…

Acute kidney injury

Artificial Intelligence Help Accurately Predict Acute Kidney Injury

Many burn victims suffer acute kidney injury (AKI), but early recognition of AKI remains challenging. Now an Artificial Intelligence / Machine Learning (AI/ML) model developed at UC Davis Health and reported in a new study can predict acute kidney injury quicker and more accurately than ever. The ability to predict AKI in burn patients using…

Chronic Kidney Disease

Continual, Significant Gaps Are Seen In Chronic Kidney Disease Patients

High prevalence of uncontrolled hypertension and diabetes is seen in chronic kidney disease (CKD)  patients; as well as statin use below the recommended guidelines for cholesterol control; according to a study by researchers at UC San Francisco. But effective treatments exist for the more than 30 million Americans with CKD; nearly 50 % of such…

Kidney

Presence Of Antibody Decease Kidney Donors Tied To Graft Failure

A study done by researchers from the Netherlands has tied greater risk of allograft loss; in kidney transplants with one protein found in deceased donor kidneys. However, auto-antibodies against Rho GDPdissociation inhibitor 2 (ARHGDIB); one of the 14 proteins reviewed in the study, only had an impact among deceased donor kidneys; not living-related kidneys, wrote…

Kidney Function

Risk Model May Predict Recovery Of Kidney Function Or Death After AKI

A risk model accurately categorized patients with an inpatient episode of acute kidney injury; into clinically distinct groups according to likelihood of either death; or recovery of kidney function and ability to discontinue dialysis after hospital discharge, according to a published study. “In addition to providing meaningful information to patients and their families; it could…

CKD Patients

Risk Of CKD Patients: Effectiveness Of Cardiovascular Therapies

The success of cardiovascular therapies, whether medical or surgical; can be influence by a CKD patient’s level of risk at baseline for cardiovascular disease, researchers conclude in  study. “Outcomes associated with cardiovascular therapies among patients with CKD differed by baseline cardiovascular risk,” David M. Charytan, MD, of the department of medicine, Brigham & Women’s Hospital, and…

Dialysis

Role Of Polyphosphate In Dialysis-Related Amyloidosis

Long-term dialysis treatment is tough on the body in many ways; but one of the most serious complications is dialysis-related amyloidosis; a disease characterized by abnormal buildup of protein aggregates called amyloid fibrils in joints, tissues and organs. Although there is no cure, recent research by Osaka University researchers sheds light; on how amyloid fibrils…

Bladder Cancer

Strain Of Common Cold Virus Target And Destroy Bladder Cancer Cells

A strain of the common cold virus has found to potentially target; infect and destroy cancer cells in patients with bladder cancer; a study in the medical journal Clinical Cancer Research reports. No trace of the cancer was found in one patient following treatment with the virus. Researchers from the University of Surrey and Royal…

Diabetic kidney disease

Diabetic Kidney Disease Progression Is Affected By HbA1c, BP

“The definition of diabetic kidney disease has expanded to include the presence of albuminuria; at any level of kidney function or renal function decline in the absence of detectable albuminuria,” Janet B. McGill, MD, Editorial Board Member and professor of medicine; and director of the fellowship in endocrinology, diabetes and metabolism at Washington University School…

Kidney Disease

Young People With Kidney Disease Prioritize Outcomes Of Daily Life

“Chronic kidney disease has devastating, long-term and wide-ranging consequences for young people and their families,” Camilla S. Hanson, PhD, of the Sydney School of Public Health at the University of Sydney and the Centre for Kidney Research, Children’s Hospital at Westmead, in Australia, and colleagues wrote. “Interventions in CKD can have profound consequences on patients and their…