All news from Nephrology

Higher eGFR

Dialysis at Higher EGFR Shows Worse Survival In Children

Earlier initiation of dialysis i.e., at a higher eGFR in adults has not yielded a survival benefit; but it has unclear whether the timing of dialysis initiation in children is associate with mortality. Dr. Erica Winnicki of the University of California, San Francisco; and colleagues used USRDS data from more than 15,000 children treated with…

Kidney transplant

Kidney Transplant Patients Are Sick And Fighting To Stay Alive

Most kidney transplant patients are extremely sick and fighting just to stay alive. That fight does not come to an end once they have successfully transplanted organ rejection is a serious potential complication; and patients must be vigilant about taking their immunosuppressive drugs; to keep their bodies from rejecting this new foreign object. However, new…

Brain aneurysms

Polycystic Kidney Disease Patients Screened For Brain Aneurysms

Autosomal dominant polycystic kidney disease (ADPKD) is characterized by progressive development of kidney cysts; as well as abnormalities outside the kidneys; including brain aneurysms or weaknesses in blood vessels in the brain that balloon and fill with blood and may later rupture. A new study appearing in CJASN investigated whether patients with ADPKD; should routinely…

Obesity

Obesity May Accelerate Chronic Kidney Disease Progression

Patients with obesity had an increased risk for chronic kidney disease progression; regardless of whether they also had metabolic abnormality, according to a published study. “Recent studies have identified a unique subtype of obesity called metabolically healthy obesity; which has distinct features of low metabolic burden such as better lipid and inflammatory profiles, lower insulin…

Sleeve gastrectomy

Sleeve Gastrectomy Rates Increasing U.S. Patients With Kidney Failure

A recent analysis of trends in weight loss surgery among patients with kidney failure; and obesity reveals that sleeve gastrectomy is safe, and its use has increased in recent years. The findings, which appear in an upcoming issue of CJASN; suggest that kidney failure should not be considered a contraindication for weight loss surgery. As…

Kidney Disease

Molecular Traffic Jam May Underlie Kidney Disease

In a study of a rare disorder called MUC1 kidney disease (MKD); which the researchers showed stems from the harmful build-up of a misfolded version of a protein called MUC1 in kidney cells. Moreover, the researchers found that the cell’s failure to remove the misfolded protein; could be traced to a specific molecular step in…

Patients

Noninvasive Device Could Benefit Patients With Kidney Disease

For patients with kidney failure who need dialysis; removing fluid at the correct rate and stopping at the right time is critical. This typically requires guessing how much water to remove and carefully monitoring the patient for sudden drops in blood pressure. Currently there is no reliable, easy way to measure hydration levels in these…

Dialysis

Older Patients With Kidney Failure See Dialysis As The Only Option

A published study found older patients with advanced chronic kidney disease or ESKD; as well as their family members, lacked knowledge regarding alternatives to dialysis. According to the study authors; this lack of knowledge may limit the patient’s ability to make informed decisions about personal care. “Although increasing numbers of adults 65 years and older…

Home dialysis

Initiating Home Dialysis Narrowed: Racial And Ethnic Differences

Dialysis is a life-saving treatment for many individuals with kidney failure; either at home by the patient or at a dialysis facility by trained personnel. The use of home dialysis in the United States increased; From last 10 years due to payment reforms and educational efforts. Because it provides patients with more autonomy and flexibility;…

kidney function

Dialysis At Higher Level Of Kidney Function Linked To Kidney failure

A recent analysis of U.S. data over 2 decades indicates that children; with kidney failure are started on dialysis at higher levels of kidney function. Initiating dialysis at a higher level of kidney function was link to lower patient survival, however. The findings, which appear in an upcoming issue of JASN; suggest that asymptomatic children…