Russian researchers from the Moscow Institute of Physics and Technology, the Institute of Cell Biophysics, and elsewhere have shown an antioxidant compound known as peroxiredoxin to be effective in treating kidney injury in mice. The study in Cell and Tissue Research reports tripled survival rates in test animals treated with the chemical prior to sustaining an ischemia…
Two new studies reveal that modern machine learning a branch of artificial intelligence; in which systems learn from data, identify patterns; and make decisions may augment traditional diagnostics of kidney disease. The findings appear in an upcoming issue of JASN. Pathologists often classify various kidney diseases on the basis of visual assessments of biopsies from…
A new meta-analysis published in The Lancet Diabetes and Endocrinology has found that SGLT2 inhibitors; can reduce the risk of dialysis, transplantation; or death due to kidney disease in people with type 2 diabetes. Lead author Dr. Brendon Neuen from The George Institute for Global Health commented: “We found SGLT2 inhibitors clearly and powerfully reduce…
Academic experts and students at the University of Sheffield, working with leading charity Kidney Care UK; found that if there is no withdrawal agreement, and no reciprocal healthcare arrangements are made with EU countries before the end of October 2019; UK hemodialysis patients will not be able to travel in Europe unless they pay around…
Low body mass index (BMI) is a potential risk factor for mortality in patients on maintenance hemodialysis. This suggests the usefulness of BMI as a prognostic factor and implies the importance of nutritional status; inflammation, and oxidative stress, all of which affect BMI. They aimed to evaluate BMI changes over time and the mortality risk…
Obesity clearly associated to kidney disease in adult population; however, there is scarce evidence in children and adolescents. The aim was to compare frequency of renal damage according to the presence of overweight-obesity in children and adolescents, as well as to compare nutritional and biochemical risk factors, according to the presence of kidney alterations. Children…
Patients who die waiting for a kidneys, or who are removed from the transplant waitlist for poor health; are usually considered unfortunate victims of the ever-growing shortage of available organs. Yet a new study has found that most candidates have had multiple opportunities to receive a transplant; but the offered organs declined by their transplant…
A recently published report found early changes in both albuminuria and eGFR to be effective; and reliable end points for use in clinical trials determining chronic kidney disease progression. According to a press release from the National Kidney Foundation; these findings may accelerate clinical trials thereby quickening the approval of new therapies to slow disease…
In one of the largest and most detailed studies ever conducted; patients recruited in general practice with a diagnosis of gout were more than twice as likely to develop kidney failure than those without; according to the study led by researchers at University of Limerick’s (UL) Graduate Entry Medical School (GEMS). The largest and most…
French transplant centers would have transplanted more than 60 % about 17,500 kidneys; of the nearly 28,000 deceased-donor kidneys discarded in the United States between 2004 and 2014; according to the research team from Penn Medicine and the Paris Transplant Group. “These findings highlight the striking disparities in organ acceptance between the two countries; and…
For people with polycystic kidney disease (PKD); life can be a constant cycle of symptoms: aches and pains, abdominal swelling, kidney stones, high blood pressure. At worst, the disease frequently leads to a suite of major issues; including kidney failure, cyst growth in the liver and vascular problems, including strokes. According to the National Institutes…
A recently published study found psychiatric illnesses, common among patients with ESKD hospitalized; within their first year of dialysis treatment, were associated with higher patient mortality after discharge. “The presence of depression or anxiety associated with lower quality; of life in adult and pediatric kidney disease patients,” Paul L. Kimmel, MD,of the National Institute of…