Air Pollution

Researchers found that long-term exposure to particulate matter and nitrogen dioxide due to air pollution; as well as proximity to vehicular traffic, were associated with severity of coronary artery calcium, or the buildup of plaque in the artery walls. The study was conducted on 8,867 Chinese adults aged 25 to 92.

But the findings, published in JAMA Open Network, are significant because; while similar studies have conduct in the U.S. and Europe, this one is the first to investigate the connection between air pollution; and coronary artery calcium in China. However the country focus more recently on reducing the extremely high levels of air pollution that exist in some regions; particularly northern China.

“This study may provide evidence that coronary atherosclerosis is a pathological pathway through; which air pollution exposure increases risk of death from coronary heart disease,” said the paper’s first author, Meng Wang, assistant professor of epidemiology and environmental health in UB’s School of Public Health and Health Professions.

Air pollution standard

“This finding should contribute to an understanding of air pollutant effects worldwide; providing both much-needed, locally generated data and supportive evidence to inform the air pollution standard setting process on a global scale,” added Wang, Ph.D., who is also a faculty member in the UB RENEW (Research and Education in eNergy, Environment and Water) Institute.

Atherosclerosis refers to the build-up of plaque, or fatty deposits; in the artery walls, which, over time, restricts blood flow through the arteries. This can cause a blood clot resulting in a heart attack or stroke. “Atherosclerosis is a lifelong process. As such; the effects of air pollution exposure on atherosclerosis are likely to be chronic,” Wang explained.

If an association between this condition and air pollution becomes harmful to health. The study centered on levels of nitrogen dioxide and PM2.5, or fine particulate matter. PM2.5 are super tiny particles that can easily be inhaled; causing serious health problems, according to the U.S. Environmental Protection Agency.

Higher coronary artery calcium score

However, the study also looks at proximity to traffic and used nitrogen dioxide; as a more precise indicator of vehicular emissions. But it showed that the risk of a higher coronary artery calcium score increase; by 24.5%for every 20 micrograms per cubic meter of air increase in nitrogen dioxide.

But air pollution remains a significant issue in China. In 2015, more than 95 % of the Chinese population exposed to concentrations of PM2.5 and nitrogen dioxide greater than the minimum level of the study; according to Wang. “Since more than 40% of all deaths are attributable to cardiovascular disease; the potential contribution of air pollutants to cardiovascular disease in China is very large,” he said.

Improving air quality to the Chinese national standards of 35 and 40 micrograms per cubic meter of air for PM2.5 and nitrogen dioxide; respectively, may help people live longer, Wang said. Still, the effect of nitrogen dioxide exposure on coronary artery calcium persisted even when researchers restrict; their analysis to concentrations below 40 micrograms per cubic meter of air. “This suggests that the current air pollution standard may need to be re-evaluated,” Wang said.