All news from Medical Toxicology

Opioid abuse

Focuses On Opioid Addiction Treatment In Teens

Substance use disorders continue to rise at alarming rates among adolescents; with opioid abuse contributing to this significant public health problem. A Penn State researcher and his team will receive over $1.8 million over three years from the National Institute on Drug Abuse to investigate how opioid; use is treating in adolescence. According to principal…

Erectile Dysfunction Drugs

Side Effects: Erectile Dysfunction Drugs Provides

The phosphodiesterase (PDE) family displays a conserved catalytic phosphohydrolase domain; whose activity is by diverse domain structures and regulatory mechanisms. Because of their association with various pathologies and distinct cellular and subcellular distributions; PDEs are targets of several widely use drugs and remain a major target for drug development. Most structure-activity relationship studies have so…

Hypotension

Drug Interaction May Causes Hypotension

A drug interaction is an unintentional effect of using two (or more) drugs, or an interaction between a drug, and food, beverage, or supplement. It is defined as the change in efficacy or toxicity of one drug by prior; or concomitant administration of a second drug (or other active substance). There are several possible reasons for…

Acetaminophen

Common Pain Reliever May Increase Stroke Risk

Acetaminophen is one of the most widely used pain relievers. Almost 60 years of widespread use have acetaminophen a household product. It’s distributed over the counter (OTC) in most countries and judged safe by the scientific community. However, acetaminophen is also one of the most common medications involved in overdoses and is the most common…

Risk of adverse effects

Old Age Increases Risk Of Adverse Side Effects

As people get older, the more likely they are to take several different medicines on a regular basis. However, this increases the risk of adverse effects; including interactions between the various active agents. Electronic decision-support tools for doctors are a possible solution but patients themselves can also help; Andreas Sönnichsen points out. Polypharmacy patients are…

Adverse drug reactions

Gender Differences In Reports Of Adverse Drug Reactions

Adverse drug reactions (ADRs) are common in clinical practice. A study using data from medical records showed that 12% of a randomly selected sample of adults; from the general public in Sweden had an ADR in a 3-month period of any of the drugs they used. Higher numbers of ADRs have shown in studies using…

Metals In Liquor

Dangerous Levels Of Metals In Liquor Sold In Uganda

The sub-Saharan countries of Africa are currently experiencing an increase in adult mortality partly due to the heavy consumption of cheaply and widely available spirits in the region. This scenario is best illustrated by the plight of the Acoli population of Uganda, a community in which uncontrolled alcohol consumption and alcohol dependency was acquired involuntarily…

Antibiotic resistance

New Strategy To Combat Antibiotic Resistance

A new strategy to combat antibiotic resistance has emerged from a study led by researchers at Baylor College of Medicine. Published in the journal Molecular Cell, the report reveals for the first time how bacteria evolve mutations that confer antibiotic resistance and that this process can inhibited with FDA-approved drug edaravone. “Antibiotic resistance is one…

Red meat

Small Amount Of Red And Processed Meat May Harmful

Research from Loma Linda University Health in California has suggested that consuming small amounts of red or processed meat can increase the risk of death when compared to individuals following a no-meat; vegetarian diet. The study included 72,149 individuals participating in the Adventist Health Study-2 (AHS-2); a large cohort study of Seventh-day Adventist men and…

Antibiotic prescribing

Unnecessary Antibiotic Prescribing In SA

A study by researchers at Wits and the London School of Economics has revealed very high rates; of antibiotic prescribing in South Africa. Researchers in the Centre for Health Policy in the Wits School of Public Health and in the Department of Health Policy at the London School of Economics and Political Science shared the…

Opioid abuse

Long Lasting Opioid Antidote On The Horizon

Recent reports have shown a 1,000 % rise in opioid abuse (especially synthetic drug Fentanyl); in the United States over the past decade. In 2017, for example, there have been 47,000 deaths to opioid overdose; says the US Centre for Disease Control and Prevention (CDC). This has alarmed health officials with the rising number of…

Tramadol

Tramadol May Up Mortality Risk In Osteoarthritis

Few safe and effective treatments are available for patients with osteoarthritis. The main goal of medical therapy for managing osteoarthritis is to control pain while avoiding therapeutic toxicity. Tramadol, a weak opioid agonist, has considered a potential alternative to traditional opioid agonists in managing pain. Current American Academy of Orthopaedic Surgeons guidelines strongly recommended tramadol…