All news from Medical Toxicology

Prescription Drug Misuse

PREMIER Center Aims To Tackle Prescription Drug Misuse

For the first time in American history, a person is more likely to die from an accidental opioid overdose than from a car accident. That’s the alarming conclusion of a National Safety Council report earlier this year; which places the rising odds of dying accidentally from an opioid overdose at one in 96; eclipsing the…

Caffeine

Caffeine prevents: Disturbances In Respiratory Neural Control

Researchers from the Department of Pediatrics at Case Western Reserve University School of Medicine and University Hospitals Rainbow Babies and Children’s Hospital presented; results of a study that investigated whether there are any deleterious effects of prostaglandin E1 (PGE1); treatment on breathing and whether these effects would be prevented via pre-treatment with caffeine. Congenital heart…

Opioid Poisonings

Geographic Variation In Pediatric Deaths From Opioid Poisonings

A new study shines a light on pediatric opioid deaths by U.S. region; the first time a study of this nature has conducted. Findings from the study will presented during the Pediatric Academic Societies (PAS) 2019 Meeting; taking place on April 24 – May 1 in Baltimore. “Although that nearly 10,000 children and adolescents died…

Food ingredient

Food Ingredient Raise The Risk For Diabetes And Obesity

Consumption of propionate, a food ingredient that’s widely used in baked goods, animal feeds, and artificial flavorings, appears to increase levels of several hormones that are with risk of obesity and diabetes, according to new research led by Harvard T.H. Chan School of Public Health in collaboration with researchers from Brigham and Women’s Hospital and…

Heart attack

Antibiotic Use Linked To Greater Risk Of Heart Attack And Stroke

Women who take antibiotics over a long period of time are at increased risk of heart attack or stroke; according to research carried out in nearly 36,500 women. Women aged 60 or older who took antibiotics for two months or more had the greatest risk of cardiovascular disease; but the long duration of antibiotic use was…

Adverse events

Risks, Benefits Of Long-Term Drug Therapy For Osteoporosis

Long-term osteoporosis drug therapy (ODT) reduces fracture risk in women but may increase the risk for rare adverse events; research gaps surround the use of long-term drug therapies for osteoporotic fracture prevention; according to a review and position paper published online. Howard A. Fink, M.D., M.P.H., and colleagues examined the effects of long-term ODT and…

Opioid Crisis

Bosses Charged With Fueling Opioid Crisis

Two former executives of a major US pharmaceutical company charged Tuesday with fulfilling orders they knew to fraudulent during the opioid epidemic that has claimed tens of thousands of lives. It was the first time that senior or former executives have faced criminal charges in connection with distributing powerful prescription painkillers like oxycodone and fentanyl that…

CAR T-Cell Therapy

CAR T-Cell Therapy Eliminates Severe Side Effects

Chimeric antigen receptor T cells are T cells that have genetically engineered to produce an artificial T-cell receptor. Chimeric antigen receptors are bioengineered proteins that give T-cells the mechanism; to neutralize a particular protein. The receptors are termed “chimeric” because they utilize both native T-cell functions; the new antigen-recognizing functions into one receptor. An advance in…

Ribociclib

Ribociclib Breast Cancer: Survival But Also Severe Side Effects

In 2017, the German Institute for Quality and Efficiency in Health Care (IQWiG); already examined the advantages and disadvantages of palbociclib in combination with an aromatase inhibitor versus the appropriate comparator therapy in patients with HR-positive, HER2-negative, locally advanced or metastatic breast cancer. At that time, the examination concentrated on the application as initial endocrine-based…

Women dug addiction

Body Awareness Training Helps Women Recover From Drug Addiction

A novel type of body awareness training helps women recover from drug addiction; according to new research from the University of Washington. People in the study made a marked improvement, and many improvements lasted for a year. It’s the first time the mindfulness approach has studied in a large randomized trial as an adjunct treatment.…

Female Viagra

Warning On Alcohol Use With Female Viagra

A drug touted as a “female Viagra” can cause severe low blood pressure and fainting when used with alcohol, the U.S. Food and Drug Administration warns. As a result, the agency has ordered the drug’s maker Sprout Pharmaceuticals to make a safety labeling change to Addyi (flibanserin). The boxed warning, contraindication, warnings and precautions; adverse…

Topsoil

Topsoil Boosts Cognitive Difficulties In Five Year Old Boys

Soil contamination has long recognized as a contributor to lead exposure in people; is now a health concern worldwide. In a new study; researchers sought to estimate the causal effects of exposure to lead in topsoil on the cognitive ability of 5-year-olds in the United States. The study found that higher lead-in topsoil significantly increases…